{"hq_id":"hq-p-fod-000064","name":"Vanilla / Cinnamon Scented Baking Extracts","category":{"primary":"food_contact"},"product_tier":"FOD","overall_risk_level":"high","description":"Artificial baking extracts (vanilla, cinnamon, almond) containing synthetic fragrance compounds, propylene glycol, and alcohol. Used directly in food preparation, with compounds becoming part of consumed food products.","synthesis":{"derived_risk_level":"low","synthesis_confidence":0.576,"synthesis_method":"compound_composition","context_used":"human_child","context_source":"product_users","exposure_modifier":1.075,"vulnerability_escalated":true,"escalation_reason":"Child exposure group","compounds_resolved":10,"compounds_total":10,"synthesis_date":"2026-05-09","synthesis_version":"1.2.0","methodology_note":"exposure_modifier and adjusted_magnitude are computed from ALETHEIA-calibrated heuristics (route × duration × frequency multipliers, clamped to [0.5, 1.4]). Multipliers are directionally informed by EPA Exposure Factors Handbook (2011) and CalEPA OEHHA but are not regulatory consensus. See /api/methodology for full disclosure."},"hazard_summary":{"sensitive_populations":"Home bakers and consumers of baked goods containing artificial extracts","overall_risk":"high","primary_concerns":["Direct food ingredient with no removal during baking/heating. Propylene glycol vehicle compound also ingested (typical extract: 35-50% propylene glycol). Fragrance compounds survive baking temperatures (volatilization minimal at standard bake temps 350-375°F). Chronic ingestion via desserts, baked goods. Children exposed through cakes, cookies, cupcakes, pancakes 2-5+ times weekly. Cumulative exposure: 2-5 mg fragrance compounds daily from baked goods alone, plus any direct extract use (e.g., vanilla in beverages)."],"exposure_routes":"Direct ingestion as food ingredient (baked goods, desserts, beverages); Heating/baking does not fully eliminate volatile fragrance compounds; Unmetabolized excipients (propylene glycol) ingested with active compounds"},"exposure":{"users":["adult","child"],"routes":["inhalation","oral"],"contact_types":["inhalation","oral_direct"],"duration":"minutes","frequency":"daily","scenarios":["Oral/ingestion exposure during use of Vanilla / Cinnamon Scented Baking Extracts","Inhalation exposure during use of Vanilla / Cinnamon Scented Baking Extracts","Incidental mouthing or hand-to-mouth transfer by children"],"notes":"Exposure to Vanilla / Cinnamon Scented Baking Extracts occurs via inhalation, oral. Children and infants face higher exposure per body weight due to developing detoxification systems, higher surface-area-to-weight ratio, and behavioral factors (mouthing, crawling)."},"consumer_guidance":{"usage_warning":"Use pure or high-quality extracts (minimal propylene glycol). Limit baked goods containing artificial extracts to 1-2 servings per week if possible. Use real vanilla bean or pure vanilla extract (post-alcohol evaporation) if available. Read ingredient labels and avoid extracts with propylene glycol as primary vehicle.","safer_alternatives":["Pure vanilla bean (scraped directly into recipe)","Real vanilla extract (aged, without propylene glycol vehicle)","Pure plant-based extracts (almond extract from real almonds)","Omit flavoring extracts entirely; use natural spices (cinnamon, nutmeg) instead","Homemade extracts using whole plants + organic alcohol"]},"regulatory":{"applicable_regulations":[{"jurisdiction":"USA","regulation":"FDA 21 CFR Parts 170-199 (Food Contact Substances)","citation":"21 CFR 170-199","requirements":"All food-contact materials must comply with FDA regulations. Indirect food additives subject to Food Contact Notification program. Specific migration limits for regulated substances.","compliance_status":null,"effective_date":null,"enforcing_agency":"FDA","penalties":null,"source_ref":null},{"jurisdiction":"EU","regulation":"Regulation (EC) No 1935/2004 + Regulation (EU) No 10/2011","citation":"EC 1935/2004, EU 10/2011","requirements":"Framework regulation for food contact materials. Plastics must not transfer constituents to food in quantities exceeding specific migration limits. Overall migration limit 10 mg/dm2.","compliance_status":null,"effective_date":null,"enforcing_agency":null,"penalties":null,"source_ref":null}],"certifications":[{"name":"FDA 21 CFR","issuer":"FDA","standard":"21 CFR Parts 170-199","scope":"Food contact substances and indirect food additives"},{"name":"NSF/ANSI 51","issuer":"NSF International","standard":"Food Equipment Materials","scope":"Materials used in commercial food equipment"}],"labeling":{"required_disclosures":[],"prop65_warning":{"required":null,"chemicals":[],"endpoint":null,"notes":null},"ghs_labeling":{"required":null,"signal_word":null,"pictograms":[],"hazard_statements":[],"notes":null},"hidden_ingredients":{"trade_secret_protected":null,"categories_hidden":[],"estimated_count":null,"known_concerns":null,"notes":null},"notes":null},"recalls":[],"regulatory_gap":null,"notes":null},"lifecycle":{"recyclable":true,"disposal_guidance":"Recycle container by resin code if marked; check local program for food-contact items","hazardous_waste":false,"expected_lifespan":"varies"},"formulation":{"form":"liquid","key_ingredients":[{"hq_id":null,"name":"Alcohol (ethanol)","role":"solvent","concentration_pct":"35-45"},{"hq_id":null,"name":"Water","role":"carrier","concentration_pct":"45-55"},{"hq_id":null,"name":"Vanillin / Cinnamaldehyde","role":"flavoring","concentration_pct":"1-5"},{"hq_id":null,"name":"Corn syrup","role":"sweetener","concentration_pct":"2-5"},{"hq_id":null,"name":"Caramel color","role":"colorant","concentration_pct":"0.5-1"}],"certifications":[]},"materials":{"common":[],"concerning":[],"preferred":[]},"compound_composition":[{"hq_id":"hq-c-org-000702","compound_name":"Cinnamaldehyde","role":"flavoring_active","typical_concentration":"5-30%"},{"hq_id":"hq-c-org-000747","compound_name":"Methyl eugenol","role":"flavoring","typical_concentration":"0.5-3%"},{"hq_id":"hq-c-org-000745","compound_name":"Coumarin","role":"flavoring","typical_concentration":"0.5-2%"},{"hq_id":"hq-c-org-000418","compound_name":"Safrole","role":"flavoring_trace","typical_concentration":"trace"},{"hq_id":"hq-c-org-000093","compound_name":"D-Limonene","role":"flavoring","typical_concentration":"0.5-3%"},{"hq_id":"hq-c-org-000739","compound_name":"Linalool","role":"flavoring","typical_concentration":"0.1-1%"},{"hq_id":"hq-c-org-000898","compound_name":"Benzyl alcohol","role":"solvent","typical_concentration":"1-5%"},{"hq_id":"hq-c-org-000322","compound_name":"Benzoic acid","role":"preservative","typical_concentration":"0.1-0.5%"},{"hq_id":"hq-c-org-000046","compound_name":"Isopropanol (isopropyl alcohol)","role":"solvent","typical_concentration":"30-50%"},{"hq_id":"hq-c-org-000903","compound_name":"Phenethyl alcohol","role":"flavoring","typical_concentration":"0.1-0.5%"}],"identifiers":{"common_names":["vanilla / cinnamon scented baking extracts"],"aliases":[],"manufacturer":null,"brands":[]},"brand_examples":[{"brand":"Generic Mass-Market Brand A","manufacturer":"Consumer Products Corporation","market_position":"mass_market","notable":"Widely available mass-market option"},{"brand":"Generic Mass-Market Brand B","manufacturer":"Consumer Goods Ltd","market_position":"mass_market","notable":"Popular budget alternative"},{"brand":"Premium Brand A","manufacturer":"Premium Consumer Inc","market_position":"premium","notable":"Upscale premium positioning"},{"brand":"Professional Brand","manufacturer":"Professional Products Co","market_position":"professional","notable":"Professional/salon-grade option"},{"brand":"Specialty Eco-Brand","manufacturer":"Natural Products Ltd","market_position":"premium","notable":"Sustainable/natural product line"}],"brand_examples_disclaimer":"Representative branded products of this category. Concerning ingredients listed in materials.concerning[] apply to the category, not necessarily to every named brand. Specific formulations vary by SKU and may have changed since this record was written; consult the brand's current ingredient label before drawing brand-level conclusions.","sources":[{"type":"expert_curation","name":"ALETHEIA Safety Database","date":"2026-03-23"},{"type":"regulation","title":"FDA 21 CFR Parts 170-199 (Food Contact Substances) (21 CFR 170-199)","jurisdiction":"USA","citation":"21 CFR 170-199","id":"src_cbd7b1e7"},{"type":"regulation","title":"Regulation (EC) No 1935/2004 + Regulation (EU) No 10/2011 (EC 1935/2004, EU 10/2011)","jurisdiction":"EU","citation":"EC 1935/2004, EU 10/2011","id":"src_37053f5a"},{"id":"src_001","type":"database","title":"PubChem Compound CID 637511","url":"https://pubchem.ncbi.nlm.nih.gov/compound/637511","accessed":"2026-03-12","notes":"Chemical identity, properties, safety data","inherited_from_compound":"hq-c-org-000702"},{"id":"src_002","type":"epa","title":"EPA CompTox Chemicals Dashboard — DTXSID1024835","url":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID1024835","accessed":"2026-03-12","notes":"Hazard, exposure, and toxicity data","inherited_from_compound":"hq-c-org-000702"},{"id":"epa_safrole_1986","type":"regulatory","title":"US EPA: Safrole — Group B2 Probable Human Carcinogen; Hepatocarcinogenesis; DNA Adducts at Guanine; Black Pepper and Star Anise Dietary Occurrence; MDMA Precursor DEA Scheduling; EU Flavoring Restrictions","year":1986,"inherited_from_compound":"hq-c-org-000418"},{"id":"iarc_safrole_vol1_1972","type":"iarc_monograph","title":"IARC Monographs Volume 1: Some Inorganic Substances, Chlorinated Hydrocarbons, Aromatic Amines, N-Nitroso Compounds and Natural Products — Safrole Group 2B; Sassafras Oil; FDA Root Beer Flavoring Ban 1960; Hepatocellular Carcinoma in Rodents; 1'-Hydroxysafrole Mechanism","year":1972,"inherited_from_compound":"hq-c-org-000418"},{"id":"fda_limonene_gras","type":"regulatory","title":"US FDA: D-Limonene — GRAS Determination, Food Additive Status, and Flavor Safety Assessment","year":2018,"inherited_from_compound":"hq-c-org-000093"},{"id":"aspca_apcc_limonene","type":"veterinary","title":"ASPCA Animal Poison Control Center: D-Limonene and Citrus Oil Toxicosis — Clinical Management in Dogs and Cats","year":2022,"inherited_from_compound":"hq-c-org-000093"},{"id":"efsa_benzoic_acid_2016","type":"regulatory","title":"EFSA ANS Panel: Re-evaluation of Benzoic Acid (E 210) — ADI 5 mg/kg bw/day; hippuric acid metabolism; GNAT glycine conjugation; benzene formation; benzyl alcohol neonatal gasping syndrome; dietary exposure (2016)","year":2016,"inherited_from_compound":"hq-c-org-000322"},{"id":"fda_gras_benzoic_acid","type":"regulatory","title":"FDA GRAS: Benzoic Acid — food preservative pH <4.5; antimicrobial mechanism; Whitfield's ointment; oral LD50 1700–3000 mg/kg; natural occurrence in cranberries/prunes; sodium benzoate relationship (2021)","year":2021,"inherited_from_compound":"hq-c-org-000322"},{"id":"atsdr_ipa","type":"report","title":"ATSDR Toxicological Profile for Isopropyl Alcohol","year":2020,"inherited_from_compound":"hq-c-org-000046"},{"id":"epa_ipa_iris","type":"regulatory","title":"US EPA IRIS: Isopropanol — Reference Dose and Review","year":1993,"inherited_from_compound":"hq-c-org-000046"}],"meta":{"schema_version":"4.0.0","last_updated":"2026-03-25","timestamp":"2026-05-13T22:22:52.536Z"}}