{"hq_id":"hq-p-bdy-000043","name":"Liquid hand soap","category":{"primary":"personal_care","secondary":"hygiene","tags":["hand soap","antibacterial","daily use"]},"product_tier":"BDY","overall_risk_level":"low","description":"Liquid hand soap for daily handwashing. Contains surfactants, preservatives, fragrance, and moisturizers. Used multiple times daily by virtually every consumer.","synthesis":{"derived_risk_level":"moderate","synthesis_confidence":0.88,"synthesis_method":"compound_composition","context_used":"human_child","context_source":"product_users","exposure_modifier":1,"vulnerability_escalated":true,"escalation_reason":"Child exposure group","compounds_resolved":6,"compounds_total":6,"synthesis_date":"2026-03-27","synthesis_version":"1.0.0"},"hazard_summary":{"overall_risk":"low","primary_concerns":["Tetrasodium EDTA (Na4EDTA / Edetate sodium / cosmetic chelator): carcinogenicity concern (Not classified as carcinogen)","Tetrasodium EDTA (Na4EDTA / Edetate sodium / cosmetic chelator): endocrine disruption concern (Not classified; CIR (Cosmetic Ingredient Review) panel assessed as safe in current use levels)"],"sensitive_populations":"","exposure_routes":""},"exposure":{"routes":["dermal","inhalation"],"contact_types":["dermal","ocular"],"users":["adult","child","elderly"],"duration":"seconds","frequency":"multiple_daily","scenarios":["Incidental mouthing or hand-to-mouth transfer by children"],"notes":"Exposure to Liquid hand soap occurs via dermal, inhalation. Children and infants face higher exposure per body weight due to developing detoxification systems, higher surface-area-to-weight ratio, and behavioral factors (mouthing, crawling). Key compounds of concern: Tetrasodium EDTA (Na4EDTA / Edetate sodium / cosmetic chelator)."},"consumer_guidance":{"red_flags":[{"indicator":"Contains \"Fragrance\" or \"Parfum\"","meaning":"Undisclosed blend of 50-200 chemicals","action":"Choose fragrance-free if sensitive"}],"alternatives":[{"name":"Fragrance-free castile soap","notes":"Minimal ingredients; no undisclosed fragrance"}],"green_flags":[],"what_to_ask":[],"notes":null},"regulatory":{"applicable_regulations":[{"jurisdiction":"USA","regulation":"FDA OTC Drug Monograph (if antibacterial)","requirements":"Antibacterial soaps must meet FDA final rule; triclosan/triclocarban banned in consumer washes (2017)"},{"jurisdiction":"EU","regulation":"EU Cosmetics Regulation 1223/2009","requirements":"MIT banned in leave-on; restricted in rinse-off (100ppm)"}],"certifications":[],"labeling":{},"recalls":[],"regulatory_gap":null,"notes":null},"lifecycle":{"recyclable":null,"disposal_guidance":"","hazardous_waste":null,"expected_lifespan":""},"formulation":{"form":"liquid","key_ingredients":[{"hq_id":"hq-c-org-000735","name":"Sodium Laureth Sulfate (SLES)","role":"surfactant","concentration_pct":"10-15"},{"hq_id":"hq-c-org-000317","name":"Glycerin","role":"carrier","concentration_pct":"3-5"},{"hq_id":null,"name":"Lauric Acid","role":"emulsifier","concentration_pct":"2-4"},{"hq_id":"hq-c-mix-000047","name":"Fragrance","role":"fragrance","concentration_pct":"0.5-1"},{"hq_id":"hq-c-org-000728","name":"Phenoxyethanol","role":"preservative","concentration_pct":"<0.5"},{"hq_id":null,"name":"Water","role":"solvent","concentration_pct":"75-85"}],"certifications":[]},"materials":{"common":["hq-m-chm-000012","hq-m-chm-000013"],"concerning":[{"material_id":"hq-m-chm-000012","concerns":[{"concern":"Polychlorinated Biphenyls (PCB mixture, typically Aroclor 12 (IARC 1)","exposure_route":"multiple","from_compound":"Polychlorinated Biphenyls (PCB mixture, typically Aroclor 12"},{"concern":"PCB-118 (a particularly toxic congener) (IARC 1, GHS: Warning)","exposure_route":"multiple","from_compound":"PCB-118 (a particularly toxic congener)"},{"concern":"Dioxin-like PCB congeners (PCB-77, PCB-126, PCB-169) (IARC 1, GHS: Warning)","exposure_route":"multiple","from_compound":"Dioxin-like PCB congeners (PCB-77, PCB-126, PCB-169)"}]},{"material_id":"hq-m-chm-000013","concerns":[{"concern":"PCBs (sorbed by PCP-treated wood in service) (IARC 1)","exposure_route":"multiple","from_compound":"PCBs (sorbed by PCP-treated wood in service)"},{"concern":"Dioxins and furans (PCDD/PCDF) as manufacturing contaminants (IARC 1, GHS: Danger)","exposure_route":"multiple","from_compound":"Dioxins and furans (PCDD/PCDF) as manufacturing contaminants"}]}],"preferred":["glass","stainless steel"]},"compound_composition":[{"hq_id":"hq-c-org-000735","compound_name":"Sodium laureth sulfate (SLES)","role":null,"typical_concentration":"5-15%"},{"hq_id":"hq-c-org-000717","compound_name":"Sodium lauryl sulfate (SLS)","role":null,"typical_concentration":"2-8%"},{"hq_id":"hq-c-org-000730","compound_name":"Cocamidopropyl betaine (CAPB)","role":null,"typical_concentration":"2-6%"},{"hq_id":"hq-c-org-000728","compound_name":"Phenoxyethanol","role":null,"typical_concentration":"0.5-1%"},{"hq_id":"hq-c-org-000616","compound_name":"Disodium EDTA","role":null,"typical_concentration":"0.1-0.3%"},{"hq_id":"hq-c-org-002048","compound_name":null,"role":null,"typical_concentration":null}],"identifiers":{"aliases":["{'hq_id': 'hq-p-ORPHAN-0372', 'name': 'Liquid hand soap', 'alias_type': 'duplicate'}"],"common_names":[],"manufacturer":null,"brands":[]},"brand_examples":[{"brand":"Dove Beauty Bar","manufacturer":"Unilever","market_position":"mass_market","notable":"Mass-market moisturizing soap; widely distributed"},{"brand":"Ivory","manufacturer":"Procter & Gamble","market_position":"mass_market","notable":"Classic mass-market bar soap"},{"brand":"Dial","manufacturer":"Henkel","market_position":"mass_market","notable":"Antibacterial mass-market soap"},{"brand":"Lux","manufacturer":"Unilever","market_position":"premium","notable":"Premium bath bar with essential oils"},{"brand":"Clearly Natural","manufacturer":"Clearly Natural","market_position":"premium","notable":"Natural premium soap brand"}],"sources":[{"id":"src_001","type":"regulatory","title":"FDA Consumer Antiseptic Wash Final Rule (2016)","year":2016},{"type":"regulation","title":"FDA OTC Drug Monograph (if antibacterial)","jurisdiction":"USA","id":"src_83761cf0"},{"type":"regulation","title":"EU Cosmetics Regulation 1223/2009","jurisdiction":"EU","year":2009,"id":"src_6b64feb0"},{"id":"src_002","type":"epa","title":"EPA CompTox Chemicals Dashboard — DTXSID1026031","url":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031","accessed":"2026-03-12","notes":"Hazard, exposure, and toxicity data","inherited_from_compound":"hq-c-org-000717"},{"id":"disodium_edta_e385_139-33-3_efsa2004_chelation","type":"regulatory","title":"Disodium EDTA CAS 139-33-3 Na2-EDTA C10H14N2Na2O8 E385 Chelating Agent; FDA 21 CFR 172.120 Mayonnaise ≤75 ppm 172.135 Canned Legumes 172.145 Shellfish; JECFA ADI 2.5 mg/kg/day; EFSA 2004 EFSA Journal 2:39 ADI 2.5 mg/kg/day; Log K: Ca2+ 10.7 Mg2+ 8.7 Fe3+ 25.7 Zn2+ 16.1 Metal Stability Constants; CaNa2EDTA Calcium Form E385 Pre-Loaded Calcium Reduces GI Chelation; Mineral Chelation Ca Mg Zn Fe Absorption Reduction Marginal Status Concern; IV CaEDTA Lead Poisoning Treatment Standard of Care Blood Lead >45 µg/dL; Chelation Therapy Alternative Medicine Not FDA Approved; Environmental Persistence Resistant Biological WWTP European Rivers Groundwater µg/L; Metal Mobilization Sediment Fe Cd Pb Hg; EDDS GLDA IDS Biodegradable Alternatives; Lipid Oxidation Pro-Oxidant Metal Sequestration Fe Cu; Mayonnaise Salad Dressing Canned Food Shelf Life","year":2004,"inherited_from_compound":"hq-c-org-000616"}],"meta":{"schema_version":"4.0.0","last_updated":"2026-03-25","timestamp":"2026-05-02T19:01:25.943Z"}}