{"hq_id":"hq-c-org-002083","name":"Lidocaine","context":"human_adult","timestamp":"2026-10-27T17:54:50.929Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-002083","sha256":"c86910b29009a136dffd0b762217560d05de43671de75c24d79dae62f1269e80"}]},"risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"src_001","type":"regulatory_database","url":"https://pubchem.ncbi.nlm.nih.gov/compound/3676"},{"id":"src_002","type":"regulatory_agency","url":"https://www.accessdata.fda.gov/drugsatfda_docs/label/lidocaine"},{"id":"pubchem-exp-drugbank-cid-3676","type":"database","title":"DrugBank, as recorded by PubChem (Experimental Properties, CID 3676; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/3676/JSON?heading=Experimental+Properties"}],"sources_scope":"context","derived_markers":[],"warnings":["unmapped_classification:FDA:approved prescription drug (injectable, iv) and ot","unmapped_classification:WHO:essential medicine","unmapped_classification:EMA:authorized pharmaceutical","unmapped_classification:DEA:not a controlled substance","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":9,"warnings":["unmapped_classification:FDA:approved prescription drug (injectable, iv) and ot","unmapped_classification:WHO:essential medicine","unmapped_classification:EMA:authorized pharmaceutical","unmapped_classification:DEA:not a controlled substance"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","human_infant","human_teen","human_elderly","human_pregnant","exposure_dermal","exposure_ingestion","exposure_inhalation"]}