{"hq_id":"hq-c-org-002003","name":"R-1234ze(E) (trans-1,3,3,3-Tetrafluoropropene)","context":"human_adult","timestamp":"2026-10-27T16:59:39.272Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-002003","sha256":"df8dc01b90286e957d89e8d2d9780ae9ebbae2beda56dc0c2519bd08b8cf8505"}]},"risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"r60-2026-09-24-d867-ecfr-29cfr1910.1000","type":"regulatory","title":"§ 1910.1000 Air contaminants.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-22/title-29.xml?part=1910&section=1910.1000"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"pubchem-computed-structure-cid-5708720","type":"database","title":"PubChem computed structure descriptors for CID 5708720 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/5708720"},{"id":"r60-2026-09-27-d902-ac1-synonyms","type":"database","title":"D-902 AC1 capture: 2026-09-27-d902-ac1-synonyms (POST, HTTP 200)","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/synonyms/JSON"},{"id":"r60-2026-10-02-d968-epa-tsca-inventory-csv","type":"regulatory","title":"CSV Non-CBI TSCA Inventory (zip), July 2026 (EPA)","url":"https://www.epa.gov/system/files/other-files/2026-05/csv-non-cbi-tsca-inventory.zip"}],"sources_scope":"record","derived_markers":[],"warnings":["unmapped_classification:EU F GAS:exempt from phase-down (gwp<150). preferred replac","unmapped_classification:EPA SNAP:listed as acceptable substitute in multiple end us","unmapped_classification:ASHRAE 34:a2l safety classification","unmapped_classification:REACH:registered under eu reach","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":10,"warnings":["unmapped_classification:EU F GAS:exempt from phase-down (gwp<150). preferred replac","unmapped_classification:EPA SNAP:listed as acceptable substitute in multiple end us","unmapped_classification:ASHRAE 34:a2l safety classification","unmapped_classification:REACH:registered under eu reach"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","dog","cat","environmental","human_teen","human_elderly","human_infant","human_pregnant"]}