{"hq_id":"hq-c-org-001006","name":"Cumene","context":"human_adult","timestamp":"2026-08-28T02:42:50.424Z","risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"src_001","type":"database","title":"PubChem","year":2026},{"id":"iarc_101_cumene","type":"regulatory","title":"IARC Monograph Volume 101 — Cumene (Group 2B — Possibly carcinogenic to humans)","year":2013},{"id":"ntp_roc_cumene","type":"regulatory","title":"NTP 14th Report on Carcinogens — Cumene (Reasonably Anticipated to be a Human Carcinogen)","year":2014},{"id":"epa_cumene_iris","type":"regulatory","title":"EPA IRIS — Cumene Toxicological Review (RfC framework, kidney + liver endpoints)","year":1997},{"id":"niosh_cumene_pocket_guide","type":"regulatory","title":"NIOSH Pocket Guide to Chemical Hazards — Cumene (CAS 98-82-8)","year":2019},{"id":"osha_cumene_pel","type":"regulatory","title":"OSHA PEL — Cumene (29 CFR 1910.1000 Table Z-1, with skin notation)","year":2020},{"id":"atsdr_cumene_tox_profile","type":"regulatory","title":"ATSDR Toxicological Profile — Cumene","year":2014},{"id":"echa_reach_cumene","type":"regulatory","title":"ECHA REACH Dossier — Cumene harmonised classification (H226 flammable, H332 inhalation, H304 aspiration, H411 aquatic)","year":2020}],"sources_scope":"record","warnings":["single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":8},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","exposure_dermal","exposure_ocular","exposure_inhalation","occupational_exposure","human_teen","human_elderly","human_infant","human_pregnant","aquatic_life","exposure_ingestion"]}