{"hq_id":"hq-c-org-000748","name":"Musk ambrette","context":"human_adult","timestamp":"2026-10-27T20:57:12.461Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000748","sha256":"86ad819fc72d66cdf58c26dad300eb96d4287d81f6f6964e80a779dea47a4578"}]},"risk_level":"severe","risk_profile":{"magnitude":{"mean":0.775,"weightedMean":0.775,"std_dev":0,"confidence_interval_95":[0.775,0.775],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.775,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates severe risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"src_001","type":"database","title":"PubChem Compound Database","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/6753"},{"id":"r60-2026-09-30-d907-2caff01ada","type":"regulatory","title":"Regulation (EC) No 1223/2009 on cosmetic products, consolidated version of 24.4.2024 (EUR-Lex), Annex II","url":"https://eur-lex.europa.eu/legal-content/EN/TXT/HTML/?uri=CELEX:02009R1223-20240424"},{"id":"r60-2026-10-01-ifra-std-168","type":"regulatory","title":"IFRA Standard (Amendment 40): Musk ambrette","url":"https://d3t14p1xronwr0.cloudfront.net/docs/standards/IFRA_STD_168.pdf"},{"id":"pubchem-computed-cid-6753","type":"database","title":"PubChem computed properties for CID 6753 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/6753"},{"id":"r60-2026-10-08-d974-tedx-list-full-export","type":"reference_database","title":"TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018)","url":"https://endocrinedisruption.org/interactive-tools/tedx-list-of-potential-endocrine-disruptors/search-the-tedx-list"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"src_pubchem_exp_6753","type":"pubchem","title":"PubChem: Experimental Properties section (CID 6753)","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/6753/JSON?heading=Experimental+Properties"},{"id":"ctx_pred_dtxsid7025689","type":"reference","title":"EPA CompTox CTX API: predicted properties for DTXSID7025689 (Musk ambrette)","url":"https://comptox.epa.gov/ctx-api/chemical/property/predicted/search/by-dtxsid/DTXSID7025689"},{"id":"pubchem-computed-structure-cid-6753","type":"database","title":"PubChem computed structure descriptors for CID 6753 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/6753"}],"sources_scope":"record","derived_markers":[],"warnings":["unmapped_classification:EU:banned in cosmetics (cosmetics regulation (ec) no ","unmapped_classification:EDC Assessment:suspected endocrine disruptor","unmapped_classification:IFRA:prohibition","unmapped_classification:EU_COSMETICS:banned","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":13,"warnings":["unmapped_classification:EU:banned in cosmetics (cosmetics regulation (ec) no ","unmapped_classification:EDC Assessment:suspected endocrine disruptor","unmapped_classification:IFRA:prohibition","unmapped_classification:EU_COSMETICS:banned"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","aquatic_life","human_child","human_teen","human_elderly","human_infant","human_pregnant"]}