{"hq_id":"hq-c-org-000747","name":"Methyl eugenol","context":"human_adult","timestamp":"2026-08-28T02:45:20.812Z","risk_level":"high","risk_profile":{"magnitude":{"mean":0.612442,"weightedMean":0.612442,"std_dev":0.1097,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"IARC","year":2024,"value":0.7,"weight":0.5494},{"source":"HQ_DIRECT","year":2026,"value":0.475,"weight":0.35}]},"confidence":{"mean":0.695473,"weightedMean":0.695473,"std_dev":0.156018,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"IARC","year":2024,"value":0.82,"weight":0.5494}]},"recency":{"mean":0.798419,"weightedMean":0.798419,"std_dev":0.160894,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"IARC","year":2024,"value":0.67,"weight":0.5494}]},"methodology":{"mean":0.883256,"weightedMean":0.883256,"std_dev":0.146267,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"IARC","year":2024,"value":1,"weight":0.5494}]},"specificity":{"mean":0.816155,"weightedMean":0.816155,"std_dev":0.082885,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"IARC","year":2024,"value":0.75,"weight":0.5494}]},"consensus":{"exists":false,"strength":0.268667,"disagreement_magnitude":0.27598,"warning":"limited_synthesis"}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. IARC classifies as higher risk (70th percentile), while HQ_DIRECT concludes lower risk (48th percentile).","confidence_note":"Moderate-quality evidence base.","context_note":null,"warning":"limited_synthesis"},"sources":[{"id":"src_001","type":"database","title":"PubChem Compound Database","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/7127"}],"sources_scope":"record","warnings":["unmapped_classification:EDC Assessment:suspected endocrine disruptor","limited_synthesis"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":2,"db_version":7,"warnings":["unmapped_classification:EDC Assessment:suspected endocrine disruptor"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","exposure_dermal","human_pregnant","exposure_inhalation","human_teen","human_elderly","human_infant","exposure_ingestion","exposure_ocular","occupational_exposure"]}