{"hq_id":"hq-c-org-000746","name":"Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral)","context":"human_adult","timestamp":"2026-10-27T20:54:23.414Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000746","sha256":"655a6a8abf6fb876fb2f128744736dd7ed17bba5f90dfb57bfcde0934f51cea1"}]},"risk_level":"high","risk_profile":{"magnitude":{"mean":0.625,"weightedMean":0.625,"std_dev":0,"confidence_interval_95":[0.625,0.625],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.625,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates high risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"src_001","type":"database","title":"PubChem Compound Database","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/91604"},{"id":"r60-2026-09-30-d907-2caff01ada","type":"regulatory","title":"Regulation (EC) No 1223/2009 on cosmetic products, consolidated version of 24.4.2024 (EUR-Lex), Annex II","url":"https://eur-lex.europa.eu/legal-content/EN/TXT/HTML/?uri=CELEX:02009R1223-20240424"},{"id":"r60-2026-10-01-ifra-std-044","type":"regulatory","title":"IFRA Standard (Amendment 49): 3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC)","url":"https://d3t14p1xronwr0.cloudfront.net/docs/standards/IFRA_STD_044.pdf"},{"id":"pubchem-computed-cid-91604","type":"database","title":"PubChem computed properties for CID 91604 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/91604"},{"id":"r60-2026-09-26-d867-cc1-eurlex-cellar-02008R1272-20260701","type":"regulatory","title":"Consolidated TEXT: 32008R1272 — EN — 01.07.2026 (Regulation (EC) No 1272/2008, CLP; the consolidation applicable on 2026-09-26)","url":"https://publications.europa.eu/resource/celex/02008R1272-20260701"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"r60-2026-10-01-echa-annex-vi-clp-table-atp23-xlsx","type":"regulatory","title":"ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP)","url":"https://echa.europa.eu/documents/10162/17218/annex_vi_clp_table_atp23_en.xlsx/b3816c13-81a3-816d-773a-62e88c4e2700?t=1761727004499"},{"id":"pubchem-computed-structure-cid-91604","type":"database","title":"PubChem computed structure descriptors for CID 91604 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/91604"}],"sources_scope":"record","derived_markers":[],"warnings":["unmapped_classification:EU:banned in cosmetics (cosmetics regulation (ec) no ","unmapped_classification:IFRA:restriction","unmapped_classification:EU_COSMETICS:banned","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":11,"warnings":["unmapped_classification:EU:banned in cosmetics (cosmetics regulation (ec) no ","unmapped_classification:IFRA:restriction","unmapped_classification:EU_COSMETICS:banned"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant"]}