{"hq_id":"hq-c-org-000680","name":"Sodium dichromate","context":"human_adult","timestamp":"2026-10-27T19:56:43.888Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000680","sha256":"c05038e8b995d23993f93978f084b034c79d866fbae27e09b08f3bd193d637e4"}]},"risk_level":"extreme","risk_profile":{"magnitude":{"mean":0.9,"weightedMean":0.9,"std_dev":0.05,"confidence_interval_95":[0.85,0.95],"source_positions":[{"source":"NTP","year":2021,"value":0.85,"weight":0.41},{"source":"IARC","year":2012,"value":0.95,"weight":0.41}]},"confidence":{"mean":0.82,"weightedMean":0.82,"std_dev":0,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"NTP","year":2021,"value":0.82,"weight":0.41},{"source":"IARC","year":2012,"value":0.82,"weight":0.41}]},"recency":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"NTP","year":2021,"value":0.5,"weight":0.41},{"source":"IARC","year":2012,"value":0.5,"weight":0.41}]},"methodology":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"NTP","year":2021,"value":1,"weight":0.41},{"source":"IARC","year":2012,"value":1,"weight":0.41}]},"specificity":{"mean":0.75,"weightedMean":0.75,"std_dev":0,"confidence_interval_95":[0.75,0.75],"source_positions":[{"source":"NTP","year":2021,"value":0.75,"weight":0.41},{"source":"IARC","year":2012,"value":0.75,"weight":0.41}]},"consensus":{"exists":true,"strength":0.666667,"disagreement_magnitude":0.044721,"warning":"limited_synthesis"}},"interpretation":{"summary":"Sources show consensus (strength: 67%). Agreement on extreme risk.","confidence_note":"High-quality evidence exists across sources.","context_note":null,"warning":"limited_synthesis"},"sources":[{"id":"iarc_100c_chromium_vi","type":"regulatory","title":"IARC Monographs Volume 100C: Arsenic, Metals, Fibres, and Dusts","year":2012,"url":"https://www.ncbi.nlm.nih.gov/books/NBK304377/"},{"id":"niosh_chromium_vi_pocket_guide","type":"regulatory","title":"NIOSH Pocket Guide to Chemical Hazards — Hexavalent chromium","year":2019,"url":"https://www.cdc.gov/niosh/npg/npgd0138.html"},{"id":"osha_chromium_vi_standard","type":"regulatory","title":"OSHA Hexavalent Chromium Standard 29 CFR 1910.1026","year":2020,"url":"https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.1026"},{"id":"epa_chromium_vi_iris","type":"regulatory","title":"EPA IRIS — Chromium (VI) Toxicological Review","year":1998,"url":"https://cfpub.epa.gov/ncea/iris2/chemicalLanding.cfm?substance_nmbr=144"},{"id":"prop65_chromium_vi","type":"regulatory","title":"California Prop 65 — Chromium (hexavalent compounds, cancer + reproductive)","year":1987,"url":"https://oehha.ca.gov/proposition-65/chemicals/chromium-hexavalent-compounds"},{"id":"src_ntp_roc15_crvi","type":"regulatory","title":"NTP Report on Carcinogens, Fifteenth Edition — Chromium Hexavalent Compounds (Known to be human carcinogens)","url":"https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/chromiumhexavalentcompounds.pdf"},{"id":"src_eu_clp_annex_vi","type":"regulatory","title":"Regulation (EC) No 1272/2008 (CLP), Annex VI harmonised classification — sodium dichromate (index 024-004-00-7)","url":"https://publications.europa.eu/resource/celex/02008R1272-20260701"},{"id":"r60-2026-09-24-d869-iarc-monographs-available","type":"regulatory","title":"IARC Monographs — Monographs available (index)","year":2026,"url":"https://monographs.iarc.who.int/monographs-available/"},{"id":"r60-2026-10-01-echa-annex-vi-clp-table-atp23-xlsx","type":"regulatory","title":"ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP)","url":"https://echa.europa.eu/documents/10162/17218/annex_vi_clp_table_atp23_en.xlsx/b3816c13-81a3-816d-773a-62e88c4e2700?t=1761727004499"},{"id":"r60-2026-09-26-d867-cc1-eurlex-cellar-02008R1272-20260701","type":"regulatory","title":"Consolidated TEXT: 32008R1272 — EN — 01.07.2026 (Regulation (EC) No 1272/2008, CLP; the consolidation applicable on 2026-09-26)","url":"https://publications.europa.eu/resource/celex/02008R1272-20260701"},{"id":"r60-2026-09-24-d867-ecfr-29cfr1910.1026","type":"regulatory","title":"29 CFR 1910.1026 Chromium (VI) — eCFR full-text XML, 2026-09-22","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-22/title-29.xml?part=1910&section=1910.1026"},{"id":"r60-2026-09-24-d872-sodium-dichromate-pubchem-cids-props","type":"regulatory","title":"PubChem PUG-REST properties (Title, formula, InChIKey) for CID 25408,246397,131843637,24488,108005","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/25408,246397,131843637,24488,108005/property/Title,MolecularFormula,InChIKey/JSON"},{"id":"r60-2026-09-24-d872-sodium-dichromate-comptox-detail-DTXSID8021274","type":"regulatory","title":"EPA CompTox Dashboard chemical detail DTXSID8021274 (Sodium dichromate)","url":"https://comptox.epa.gov/dashboard-api/ccdapp2/chemical-detail/search/by-dsstoxsid?id=DTXSID8021274"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"pubchem-exp-cameo-chemicals-cid-25408","type":"database","title":"CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 25408; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/25408/JSON?heading=Experimental+Properties"},{"id":"pubchem-exp-hazardous-substances-data-bank-cid-25408","type":"database","title":"Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 25408; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/25408/JSON?heading=Experimental+Properties"}],"sources_scope":"record","derived_markers":[],"warnings":["year_inferred:NTP:2021","limited_synthesis"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":2,"db_version":41,"warnings":["year_inferred:NTP:2021"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_elderly","exposure_ocular","occupational_exposure"]}