{"hq_id":"hq-c-org-000630","name":"Tremolite Asbestos","context":"human_adult","timestamp":"2026-08-28T02:57:28.757Z","risk_level":"extreme","risk_profile":{"magnitude":{"mean":0.95,"weightedMean":0.95,"std_dev":0,"confidence_interval_95":[0.95,0.95],"source_positions":[{"source":"IARC","year":2012,"value":0.95,"weight":0.41}]},"confidence":{"mean":0.82,"weightedMean":0.82,"std_dev":0,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"IARC","year":2012,"value":0.82,"weight":0.41}]},"recency":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"IARC","year":2012,"value":0.5,"weight":0.41}]},"methodology":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"IARC","year":2012,"value":1,"weight":0.41}]},"specificity":{"mean":0.75,"weightedMean":0.75,"std_dev":0,"confidence_interval_95":[0.75,0.75],"source_positions":[{"source":"IARC","year":2012,"value":0.75,"weight":0.41}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (IARC, 2012) indicates high risk.","confidence_note":"High-quality evidence exists across sources. Disagreement reflects methodological and interpretive differences, not data quality issues.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"src_001","type":"regulatory","title":"IARC Monographs Supplement 7 (1987) — Asbestos (Group 1)","year":1987,"url":"https://inchem.org/documents/iarc/suppl7/asbestos.html"},{"id":"src_002","type":"regulatory","title":"FDA Testing of J&J Talc Lots for Asbestos Contamination (2019 Report)","year":2019,"url":"https://www.fda.gov/food/hfp-constituent-updates/baby-powder-manufacturer-voluntarily-recalls-product-asbestos"},{"id":"src_004","type":"journal","title":"Mesothelioma risk among those exposed to chrysotile asbestos only and mixtures that include amphibole: a case–control study in the USA, 1975–1980","year":2020,"url":"https://pubmed.ncbi.nlm.nih.gov/33087407/"},{"id":"src_jnj_reuters_2018","type":"investigative_journalism","title":"Johnson & Johnson knew for decades that asbestos lurked in its Baby Powder","year":2018,"url":"https://www.reuters.com/investigates/special-report/johnsonandjohnson-cancer/"},{"id":"src_jnj_settlement_2023","type":"court_record","title":"LTL Management bankruptcy reorganization — proposed J&J talc settlement","year":2023,"url":"https://www.npr.org/2023/04/05/1168110404/johnson-proposes-to-settle-talcum-powder-lawsuits"},{"id":"iarc_100c_asbestos","type":"regulatory","title":"IARC Monographs Volume 100C (2012) — Asbestos (all forms) (Group 1)","year":2012,"url":"https://www.ncbi.nlm.nih.gov/books/NBK304374/"}],"sources_scope":"record","warnings":["single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":30},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","human_teen","human_elderly","human_infant","human_pregnant"]}