{"hq_id":"hq-c-org-000624","name":"Perfluoroheptanoic acid (PFHpA)","context":"human_adult","timestamp":"2026-08-28T01:33:11.653Z","risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"pfhpa_375-85-9_c7_pfca_intermediate_chain_eu_20pfas_ucmr5","type":"regulatory","title":"PFHpA Perfluoroheptanoic acid CAS 375-85-9 C7HF13O2 Not IARC Classified; C7 Intermediate Short-Chain (C4-C6) vs Long-Chain (C8+) PFAS Category; ECHA REACH Long-Chain PFCA C7-C18 Definition vs EPA Short vs Long-Chain; Serum Half-Life ~1-2 Years Intermediate PFHxA vs PFOA; PPARα Hepatotoxicity Developmental Thyroid Rodent Potency Intermediate; 6:2 FTOH 7:1 FTOH 8:2 FTOH Atmospheric OH Radical Degradation Precursor; Arctic Snow Ice Remote Atmospheric Deposition; EU DWD 2020/2184 Sum 20 PFAS 0.1 µg/L; EPA UCMR5 EPA Method 537.1 Monitoring; No April 2024 US MCL; WHO 2022 Drinking Water Guidelines PFHpA Included; EU REACH Universal PFAS Restriction 2023 Proposal All PFAS; EU EFSA Sum 20 PFAS Exposure Assessment Development; REACH 2017/1000 C9-C14 PFCA Restriction PFHpA Not Explicitly Covered; Marine Fish Seafood ng/g Levels AFFF Contamination Proximity","year":2024}],"sources_scope":"record","warnings":["unmapped_classification:IARC:iarc — insufficient data for classification — perf","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":39,"warnings":["unmapped_classification:IARC:iarc — insufficient data for classification — perf"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant"]}