{"hq_id":"hq-c-org-000623","name":"6:2 Fluorotelomer sulfonate (6:2 FTS)","context":"human_adult","timestamp":"2026-08-28T02:40:51.908Z","risk_level":"moderate","risk_profile":{"magnitude":{"mean":0.3,"weightedMean":0.3,"std_dev":0,"confidence_interval_95":[0.3,0.3],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.3,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low to moderate risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"62fts_27619-97-2_afff_pfos_replacement_biotransformation_pfhxs","type":"regulatory","title":"6:2 FTS Fluorotelomer Sulfonate CAS 27619-97-2 C8H4F13O3S Not IARC Classified; 6:2 Nomenclature 6 Perfluorinated 2 Non-Fluorinated CH2CH2 Sulfonate Spacer; Post-PFOS AFFF Reformulation 2010+ Military Airport Fire Training; Biotransformation 6:2 FTSO → 6:2 FTCA → 6:2 FTUCA → PFHxA + PFBS + PFHxS Stockholm Annex A; Aerobic Soil Half-Life 10-60 Days Initial Steps Terminal PFAS Persistent Accumulate; US Military AFFF 700+ Sites 6:2 FTS µg/L-mg/L Groundwater; Australia RAAF Williamtown Tindal Civilian Airports Defence PFAS Management Plan 2017 Hundreds M AUD; EU DWD Sum 20 PFAS 0.1 µg/L; EPA Method 533 UCMR5 Monitored; Hepatotoxicity Thyroid T4 Developmental Immunotoxicity Rodent Subchronic; Cumulative Risk 6:2 FTS + Metabolites Framework; PFOS-Free AFFF Not PFAS-Free Regrettable Substitution Pattern; Polyfluoroalkyl vs Perfluoroalkyl CH2CH2 Biodegradation Site","year":2024}],"sources_scope":"record","warnings":["unmapped_classification:IARC:iarc — insufficient data for classification — 6:2 ","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":42,"warnings":["unmapped_classification:IARC:iarc — insufficient data for classification — 6:2 ","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant"]}