{"hq_id":"hq-c-org-000621","name":"Anthracene","context":"human_adult","timestamp":"2026-08-28T04:03:58.308Z","risk_level":"moderate","risk_profile":{"magnitude":{"mean":0.383256,"weightedMean":0.383256,"std_dev":0.146267,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"IARC","year":2024,"value":0.5,"weight":0.5494},{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.695473,"weightedMean":0.695473,"std_dev":0.156018,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"IARC","year":2024,"value":0.82,"weight":0.5494}]},"recency":{"mean":0.798419,"weightedMean":0.798419,"std_dev":0.160894,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"IARC","year":2024,"value":0.67,"weight":0.5494}]},"methodology":{"mean":0.883256,"weightedMean":0.883256,"std_dev":0.146267,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"IARC","year":2024,"value":1,"weight":0.5494}]},"specificity":{"mean":0.816155,"weightedMean":0.816155,"std_dev":0.082885,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"IARC","year":2024,"value":0.75,"weight":0.5494}]},"consensus":{"exists":false,"strength":0.024887,"disagreement_magnitude":0.289896,"warning":"limited_synthesis"}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. IARC classifies as higher risk (50th percentile), while HQ_DIRECT concludes lower risk (20th percentile).","confidence_note":"Moderate-quality evidence base.","context_note":null,"warning":"limited_synthesis"},"sources":[{"id":"anthracene_120-12-7_iarc_3_linear_3ring_phototoxic_wfd_svhc","type":"regulatory","title":"Anthracene (CAS 120-12-7, C14H10) — physicochemical, metabolic and ecotoxicological reference data","year":2010},{"id":"src_iarc_vol133","type":"iarc","title":"IARC Monographs Volume 133 — Anthracene, 2-bromopropane, butyl methacrylate, and dimethyl hydrogen phosphite (2024)","url":"https://www.iarc.who.int/news-events/iarc-monographs-evaluation-of-the-carcinogenicity-of-anthracene-2-bromopropane-butyl-methacrylate-and-dimethyl-hydrogen-phosphite/"}],"sources_scope":"record","warnings":["unmapped_classification:EPA CTX / IRIS:d (not classifiable as to human carcinogenicity)","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 4 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 4 positive","limited_synthesis"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":2,"db_version":47,"warnings":["unmapped_classification:EPA CTX / IRIS:d (not classifiable as to human carcinogenicity)","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 4 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 4 positive"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant","exposure_dermal","exposure_inhalation","exposure_ingestion","exposure_ocular","occupational_exposure"]}