{"hq_id":"hq-c-org-000595","name":"Sodium stearoyl-2-lactylate (SSL; E481)","context":"human_adult","timestamp":"2026-10-27T18:50:02.814Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000595","sha256":"881ad984e743019bf8f7d91601cc2be3eb31581401c586dbef3bd44ac7f49cc1"}]},"risk_level":"negligible","risk_profile":{"magnitude":{"mean":0.05,"weightedMean":0.05,"std_dev":0,"confidence_interval_95":[0.05,0.05],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.05,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates negligible risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"ssl_e481_efsa_2020","type":"regulatory","title":"Sodium Stearoyl-2-Lactylate SSL E481 CAS 25383-99-7 Anionic Emulsifier Dough Conditioner; EFSA 2013 ADI 22 mg/kg/day Re-Evaluation EFSA Journal 2013;11(5):3144; FDA GRAS 21 CFR 172.846; Stearic Acid + 2 Lactic Acid Sodium Counterion HLB 21; Hydrolysis Stearic Acid Lactic Acid Sodium Normal Metabolic Substrates; Bread Dough Conditioner Gluten Network Strengthener 0.25-0.5% Flour; Antistaling Starch Retrogradation Delay Shelf Life; Tortillas Rollability Flexibility Cracking Prevention; CSL Calcium Stearoyl-2-Lactylate E482 Analog; Not Gut Microbiome Disruption Study Ionic Emulsifier","year":2013},{"id":"r60-2026-09-30-d969-efsa-2013-3144-ssl","type":"regulatory","title":"Scientific Opinion on the re-evaluation of sodium stearoyl-2-lactylate (E 481) and calcium stearoyl-2-lactylate (E 482) as food additives","url":"https://www.efsa.europa.eu/en/efsajournal/pub/3144"},{"id":"echa-chem-reach-registrations","type":"regulatory","title":"ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances)","year":2026,"url":"https://chem.echa.europa.eu/"},{"id":"pubchem-computed-cid-23671849","type":"database","title":"PubChem computed properties for CID 23671849 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/23671849"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"r60-2026-10-02-d-955-s9-d955-s9-osha-table-z-1","type":"regulatory","title":"Permissible Exposure Limits – OSHA Annotated Table Z-1","url":"https://www.osha.gov/annotated-pels/table-z-1"},{"id":"ctx_pred_dtxsid8027872","type":"reference","title":"EPA CompTox CTX API: predicted properties for DTXSID8027872 (Sodium stearoyl-2-lactylate (SSL; E481))","url":"https://comptox.epa.gov/ctx-api/chemical/property/predicted/search/by-dtxsid/DTXSID8027872"},{"id":"pubchem-computed-structure-cid-23671849","type":"database","title":"PubChem computed structure descriptors for CID 23671849 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/23671849"}],"sources_scope":"record","derived_markers":[],"warnings":["unmapped_classification:IARC:not evaluated by iarc for carcinogenicity — sodium","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":42,"warnings":["unmapped_classification:IARC:not evaluated by iarc for carcinogenicity — sodium"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant"]}