{"hq_id":"hq-c-org-000507","name":"Ethylene","context":"human_adult","timestamp":"2026-08-28T02:55:49.096Z","risk_level":"low","risk_profile":{"magnitude":{"mean":0.226974,"weightedMean":0.226974,"std_dev":0.024922,"confidence_interval_95":[0.25,0.25],"source_positions":[{"source":"IARC","year":1994,"value":0.25,"weight":0.41},{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.672632,"weightedMean":0.672632,"std_dev":0.159501,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"IARC","year":1994,"value":0.82,"weight":0.41}]},"recency":{"mean":0.730263,"weightedMean":0.730263,"std_dev":0.24922,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"IARC","year":1994,"value":0.5,"weight":0.41}]},"methodology":{"mean":0.861842,"weightedMean":0.861842,"std_dev":0.149532,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"IARC","year":1994,"value":1,"weight":0.41}]},"specificity":{"mean":0.828289,"weightedMean":0.828289,"std_dev":0.084735,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"IARC","year":1994,"value":0.75,"weight":0.41}]},"consensus":{"exists":false,"strength":0.833853,"disagreement_magnitude":0.307831,"warning":"limited_synthesis"}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. IARC classifies as higher risk (25th percentile), while HQ_DIRECT concludes lower risk (20th percentile).","confidence_note":"Moderate-quality evidence base.","context_note":null,"warning":"limited_synthesis"},"sources":[{"id":"iarc_vol60_1994_ethylene_group3","type":"regulatory","title":"IARC Monographs Vol 60 1994: Ethylene Group 3 Not Classifiable; Distinct From Ethylene Oxide Group 1; Endogenous Plant Hormone Fruit Ripening; Petrochemical Building Block; Minor Mammalian EO Metabolite; No NTP EPA EFSA Carcinogenicity Classification","year":1994}],"sources_scope":"record","warnings":["unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 0 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 0 positive","limited_synthesis"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":2,"db_version":44,"warnings":["unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 0 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 0 positive"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant"]}