{"hq_id":"hq-c-org-000467","name":"Spinetoram","context":"human_adult","timestamp":"2026-10-27T20:52:56.321Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000467","sha256":"b063406143cbaa486e1822fb0b1f7be9ac349a1616d5b5c84476d12559734f4b"}]},"risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"epa_spinetoram_delegate_registration_2021","type":"regulatory","title":"US EPA FIFRA Biopesticide Spinetoram Delegate WG Radiant SC Registration 2021: Not Likely Carcinogenic; LD50 ~2579 mg/kg; OMRI Organic Listed; Semi-synthetic Spinosyn J L; Bee Evening Application Restriction; High Koc Low Aquatic Mobility","year":2021},{"id":"efsa_spinetoram_peer_review_2020","type":"regulatory","title":"EFSA Spinetoram Peer Review 2020: Not Carcinogenic Not Genotoxic; ADI Established; Low Mammalian Toxicity; Daphnia EC50 0.0153 mg/L Highly Toxic Crustacean; Organic Approval Basis; Broader Spectrum vs Spinosad","year":2020},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"r60-2026-10-02-d-955-s9-d955-s9-osha-table-z-1","type":"regulatory","title":"Permissible Exposure Limits – OSHA Annotated Table Z-1","url":"https://www.osha.gov/annotated-pels/table-z-1"},{"id":"doc-2026-10-02-d975-toxrefdb-3-0-pod-csv","type":"database","title":"EPA ToxRefDB 3.0 point-of-departure release (pod.csv)","url":"https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07?dataset=61147fefe4b0856fdc65639b&space=&folder=6850327be4b096bca8848301"},{"id":"pubchem-computed-cid-53297414","type":"database","title":"PubChem computed properties for CID 53297414 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/53297414"},{"id":"d974-o14-2026-10-03-d968-ecfr-40cfr180-s180.635","type":"regulatory","title":"40 CFR Part 180 (eCFR text as of 24 September 2026): § 180.635 Spinetoram; tolerances for residues.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-25/title-40.xml?part=180"},{"id":"ctx_pred_dtxsid3052854","type":"reference","title":"EPA CompTox CTX API: predicted properties for DTXSID3052854 (Spinetoram)","url":"https://comptox.epa.gov/ctx-api/chemical/property/predicted/search/by-dtxsid/DTXSID3052854"},{"id":"pubchem-computed-structure-cid-53297414","type":"database","title":"PubChem computed structure descriptors for CID 53297414 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/53297414"}],"sources_scope":"record","derived_markers":[],"warnings":["unmapped_classification:US EPA (FIFRA/biopesticide registration):not likely to be carcinogenic to humans; registere","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":40,"warnings":["unmapped_classification:US EPA (FIFRA/biopesticide registration):not likely to be carcinogenic to humans; registere"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","pollinators","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant","agricultural_worker"]}