{"hq_id":"hq-c-org-000466","name":"Emamectin benzoate","context":"human_adult","timestamp":"2026-10-27T20:52:16.615Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000466","sha256":"3dfaf736d014550fade2294920e0a89c01f8dff465f0b6dd4c893093c540277c"}]},"risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"epa_emamectin_proclaim_registration_2018","type":"regulatory","title":"US EPA FIFRA Emamectin Benzoate Proclaim Registration 2018: Not Likely Carcinogenic; LD50 ~76 mg/kg Moderately Toxic; Restricted Entry Interval 12h; GluCl Invertebrate Selective; Blood-Brain Barrier Avermectin; Daphnia EC50 0.0023 mg/L Extremely Toxic Aquatic","year":2018},{"id":"emamectin_aquaculture_slice_sea_lice","type":"regulatory","title":"Emamectin Benzoate Slice Aquaculture Sea Lice Atlantic Salmon: Marine Invertebrate Crustacean Non-target Risk; Mysid Shrimp LC50 0.0012 mg/L; EU Aquaculture Veterinary Medicine Assessment; Lobster Crab Shrimp Adjacent Waters Risk","year":2020},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"r60-2026-10-02-d-955-s9-d955-s9-osha-table-z-1","type":"regulatory","title":"Permissible Exposure Limits – OSHA Annotated Table Z-1","url":"https://www.osha.gov/annotated-pels/table-z-1"},{"id":"doc-2026-10-02-d975-toxrefdb-3-0-pod-csv","type":"database","title":"EPA ToxRefDB 3.0 point-of-departure release (pod.csv)","url":"https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07?dataset=61147fefe4b0856fdc65639b&space=&folder=6850327be4b096bca8848301"},{"id":"pubchem-computed-cid-11650986","type":"database","title":"PubChem computed properties for CID 11650986 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/11650986"},{"id":"doc-2026-10-03-d975-ecotox-ascii-09-15-2026","type":"database","title":"EPA ECOTOX Knowledgebase ASCII release ecotox_ascii_09_15_2026","url":"https://gaftp.epa.gov/ecotox/ecotox_ascii_09_15_2026.zip"},{"id":"r60-2026-09-27-d901-partBCD-comptox-cas-hq-c-org-000466","type":"database","title":"D-901 AC1 part BCD capture: 2026-09-27-d901-partBCD-comptox-cas-hq-c-org-000466","url":"https://comptox.epa.gov/dashboard-api/ccdapp1/search/chemical/equal-with-detail/137512-74-4"},{"id":"r60-2026-10-01-echa-annex-vi-clp-table-atp23-xlsx","type":"regulatory","title":"ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP)","url":"https://echa.europa.eu/documents/10162/17218/annex_vi_clp_table_atp23_en.xlsx/b3816c13-81a3-816d-773a-62e88c4e2700?t=1761727004499"},{"id":"pubchem-computed-structure-cid-11650986","type":"database","title":"PubChem computed structure descriptors for CID 11650986 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/11650986"}],"sources_scope":"record","derived_markers":[],"warnings":["unmapped_classification:US EPA (FIFRA pesticide registration):not likely to be carcinogenic to humans; registere","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":38,"warnings":["unmapped_classification:US EPA (FIFRA pesticide registration):not likely to be carcinogenic to humans; registere"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","pollinators","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant"]}