{"hq_id":"hq-c-org-000465","name":"Chlorantraniliprole","context":"human_adult","timestamp":"2026-10-27T20:56:17.064Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000465","sha256":"01a73bbfa85b226b48e166a7207f624b983191dcd0371aa507fc6c500d9c9d98"}]},"risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"epa_chlorantraniliprole_rynaxypyr_registration_2008","type":"regulatory","title":"US EPA FIFRA Chlorantraniliprole Rynaxypyr Coragen Registration 2008: Not Likely Carcinogenic; LD50 >5000 mg/kg; Ryanodine Receptor Insect 300x Selectivity; Not Reproductive Toxicant; Low Bee Contact Toxicity","year":2020},{"id":"efsa_chlorantraniliprole_peer_review_2020","type":"regulatory","title":"EFSA Chlorantraniliprole Peer Review 2020: Not Carcinogenic Not Genotoxic; ADI 0.1 mg/kg bw/day; Low Mammalian RyR Sensitivity; Larval Bee Toxicity Concern Pollen; Moderate Sediment Invertebrate Risk","year":2020},{"id":"r60-2026-09-28-d899-s3-b04-pmc-PMC7667575-efsa-2020-6300-chlorantraniliprole-it","type":"regulatory","title":"Setting of import tolerances for chlorantraniliprole in strawberries and pulses - PMC","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7667575/"},{"id":"pubchem-computed-cid-11271640","type":"database","title":"PubChem computed properties for CID 11271640 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/11271640"},{"id":"src_pubchem_tox_11271640","type":"pubchem","title":"PubChem: Toxicity section (CID 11271640)","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/11271640/JSON?heading=Toxicity"},{"id":"doc-2026-10-02-d975-toxrefdb-3-0-pod-csv","type":"database","title":"EPA ToxRefDB 3.0 point-of-departure release (pod.csv)","url":"https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07?dataset=61147fefe4b0856fdc65639b&space=&folder=6850327be4b096bca8848301"},{"id":"r60-2026-10-08-d974-tedx-list-full-export","type":"reference_database","title":"TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018)","url":"https://endocrinedisruption.org/interactive-tools/tedx-list-of-potential-endocrine-disruptors/search-the-tedx-list"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"r60-2026-10-02-d-955-s9-d955-s9-osha-table-z-1","type":"regulatory","title":"Permissible Exposure Limits – OSHA Annotated Table Z-1","url":"https://www.osha.gov/annotated-pels/table-z-1"},{"id":"pubchem-exp-hazardous-substances-data-bank-cid-11271640","type":"database","title":"Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 11271640; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/11271640/JSON?heading=Experimental+Properties"},{"id":"d974-o14-2026-10-03-d968-ecfr-40cfr180-s180.628","type":"regulatory","title":"40 CFR Part 180 (eCFR text as of 24 September 2026): § 180.628 Chlorantraniliprole; tolerances for residues.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-25/title-40.xml?part=180"},{"id":"ctx_pred_dtxsid2044345","type":"reference","title":"EPA CompTox CTX API: predicted properties for DTXSID2044345 (Chlorantraniliprole)","url":"https://comptox.epa.gov/ctx-api/chemical/property/predicted/search/by-dtxsid/DTXSID2044345"},{"id":"pubchem-computed-structure-cid-11271640","type":"database","title":"PubChem computed structure descriptors for CID 11271640 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/11271640"}],"sources_scope":"record","derived_markers":[],"warnings":["unmapped_classification:US EPA (FIFRA pesticide registration):not likely to be carcinogenic to humans; registere","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":45,"warnings":["unmapped_classification:US EPA (FIFRA pesticide registration):not likely to be carcinogenic to humans; registere"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","pollinators","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant","agricultural_worker"]}