{"hq_id":"hq-c-org-000385","name":"Chlorophacinone","context":"human_adult","timestamp":"2026-10-27T17:55:55.037Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000385","sha256":"6eda8935b10dbcecdc818289a51af9c746ef2d0922eb6b72b240b1854f044728"}]},"risk_level":"moderate","risk_profile":{"magnitude":{"mean":0.35,"weightedMean":0.35,"std_dev":0,"confidence_interval_95":[0.35,0.35],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.35,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates moderate risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"epa_rodenticide_registration_review_2020","type":"regulatory","title":"US EPA: Rodenticide Cluster Registration Review — diphacinone, chlorophacinone, warfarin (FGARs); brodifacoum, bromadiolone, difethialone, difenacoum (SGARs); bromethalin; cholecalciferol; zinc phosphide; risk assessment; use restrictions; Hawaii native bird program (2020)","year":2020},{"id":"apcc_rodenticide_2023","type":"veterinary","title":"ASPCA Animal Poison Control Center: Rodenticide Toxicosis in Dogs and Cats — anticoagulant SGARs/FGARs; bromethalin; cholecalciferol; zinc phosphide; vitamin K1 dosing; decontamination windows; INR monitoring; prognosis by rodenticide class (2023)","year":2023},{"id":"src_pubchem_tox_19402","type":"pubchem","title":"PubChem: Toxicity section (CID 19402)","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/19402/JSON?heading=Toxicity"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"pubchem-computed-cid-19402","type":"database","title":"PubChem computed properties for CID 19402 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/19402"},{"id":"doc-2026-10-02-d975-toxrefdb-3-0-pod-csv","type":"database","title":"EPA ToxRefDB 3.0 point-of-departure release (pod.csv)","url":"https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07?dataset=61147fefe4b0856fdc65639b&space=&folder=6850327be4b096bca8848301"},{"id":"pubchem-exp-cameo-chemicals-cid-19402","type":"database","title":"CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 19402; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/19402/JSON?heading=Experimental+Properties"},{"id":"pubchem-exp-hazardous-substances-data-bank-cid-19402","type":"database","title":"Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 19402; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/19402/JSON?heading=Experimental+Properties"},{"id":"pubchem-exp-ilo-who-international-chemical-safety-ca-cid-19402","type":"database","title":"ILO-WHO International Chemical Safety Cards (ICSCs), as recorded by PubChem (Experimental Properties, CID 19402; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/19402/JSON?heading=Experimental+Properties"},{"id":"ctx_pred_dtxsid2032348","type":"reference","title":"EPA CompTox CTX API: predicted properties for DTXSID2032348 (Chlorophacinone)","url":"https://comptox.epa.gov/ctx-api/chemical/property/predicted/search/by-dtxsid/DTXSID2032348"},{"id":"r60-2026-10-01-echa-annex-vi-clp-table-atp23-xlsx","type":"regulatory","title":"ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP)","url":"https://echa.europa.eu/documents/10162/17218/annex_vi_clp_table_atp23_en.xlsx/b3816c13-81a3-816d-773a-62e88c4e2700?t=1761727004499"},{"id":"pubchem-computed-structure-cid-19402","type":"database","title":"PubChem computed structure descriptors for CID 19402 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/19402"}],"sources_scope":"record","derived_markers":[],"warnings":["single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":44},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","dog","cat","aquatic_life","terrestrial_wildlife","human_teen","human_elderly","human_pregnant"]}