{"hq_id":"hq-c-org-000383","name":"Difenacoum","context":"human_adult","risk_level":"high","schema":"legacy","note":"Synthesis unavailable: compound lacks vectorizable regulatory classifications. Raw safety data returned.","data":{"risk_level":"high","summary":"Difenacoum (Neosorexa, Ratak+, Sakarat D) is a second-generation anticoagulant rodenticide (SGAR) more widely used in the UK, Europe, Australia, and New Zealand than in the US. Oral LD50 rat ~1.8 mg/kg — less potent than brodifacoum but still a highly effective SGAR requiring a single feeding for rodent control. Mechanism: VKOR inhibition with prolonged persistence. Half-life in humans and animals is weeks to months. Human poisoning cases are reported predominantly in Europe; accidental pediatric ingestions and intentional self-poisonings documented. Treatment: vitamin K1 orally for 4–6 weeks; INR monitoring; FFP for acute hemorrhage."},"meta":{"synthesis_version":"n/a","timestamp":"2026-05-01T19:43:32.759Z"}}