{"hq_id":"hq-c-org-000278","name":"Dieldrin","context":"human_adult","timestamp":"2026-06-17T20:34:55.028Z","risk_level":"high","risk_profile":{"magnitude":{"mean":0.584823,"weightedMean":0.584823,"std_dev":0.220519,"confidence_interval_95":[0.7,0.8],"source_positions":[{"source":"EPA CTX / CalEPA","year":2021,"value":0.8,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":0.7,"weight":0.30176},{"source":"HQ_DIRECT","year":2026,"value":0.3,"weight":0.35}]},"confidence":{"mean":0.70254,"weightedMean":0.70254,"std_dev":0.154241,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"EPA CTX / IARC","year":2021,"value":0.82,"weight":0.30176},{"source":"EPA CTX / CalEPA","year":2021,"value":0.82,"weight":0.30176}]},"recency":{"mean":0.599983,"weightedMean":0.599983,"std_dev":0.304626,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"EPA CTX / IARC","year":2021,"value":0.368,"weight":0.30176},{"source":"EPA CTX / CalEPA","year":2021,"value":0.368,"weight":0.30176}]},"methodology":{"mean":0.889882,"weightedMean":0.889882,"std_dev":0.144601,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"EPA CTX / IARC","year":2021,"value":1,"weight":0.30176},{"source":"EPA CTX / CalEPA","year":2021,"value":1,"weight":0.30176}]},"specificity":{"mean":0.8124,"weightedMean":0.8124,"std_dev":0.081941,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"EPA CTX / IARC","year":2021,"value":0.75,"weight":0.30176},{"source":"EPA CTX / CalEPA","year":2021,"value":0.75,"weight":0.30176}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0.395152,"warning":null}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. EPA CTX / CalEPA classifies as higher risk (80th percentile), while HQ_DIRECT concludes lower risk (30th percentile).","confidence_note":"Moderate-quality evidence base. Disagreement reflects methodological and interpretive differences, not data quality issues.","context_note":null,"warning":null},"sources":[],"warnings":["year_inferred:EPA CTX / IARC:2021","year_inferred:EPA CTX / CalEPA:2021","unmapped_classification:EDC Assessment:endocrine disruptor","unmapped_classification:EPA CTX / NIOSH:potential occupational carcinogen","unmapped_classification:EPA CTX / IRIS:b2 (probable human carcinogen - based on sufficien","unmapped_classification:EPA CTX / EPA OPP:group b2 probable human carcinogen ","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: eye dam. 1 (score: very high)","unmapped_classification:EPA CTX / Skin-Eye:skin irritation: skin corr. 1b (score: very high)"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":3,"db_version":49,"warnings":["year_inferred:EPA CTX / IARC:2021","year_inferred:EPA CTX / CalEPA:2021","unmapped_classification:EDC Assessment:endocrine disruptor","unmapped_classification:EPA CTX / NIOSH:potential occupational carcinogen","unmapped_classification:EPA CTX / IRIS:b2 (probable human carcinogen - based on sufficien","unmapped_classification:EPA CTX / EPA OPP:group b2 probable human carcinogen ","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: eye dam. 1 (score: very high)","unmapped_classification:EPA CTX / Skin-Eye:skin irritation: skin corr. 1b (score: very high)"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer"}