{"hq_id":"hq-c-org-000228","name":"Dibromochloromethane (DBCM)","context":"human_adult","timestamp":"2026-08-28T02:49:35.187Z","risk_level":"moderate","risk_profile":{"magnitude":{"mean":0.34747,"weightedMean":0.34747,"std_dev":0.105814,"confidence_interval_95":[0.3,0.5],"source_positions":[{"source":"EPA CTX / IRIS","year":2021,"value":0.5,"weight":0.30176},{"source":"HQ_DIRECT","year":2026,"value":0.3,"weight":0.35},{"source":"EPA CTX / IARC","year":2021,"value":0.25,"weight":0.30176}]},"confidence":{"mean":0.70254,"weightedMean":0.70254,"std_dev":0.154241,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"EPA CTX / IRIS","year":2021,"value":0.82,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":0.82,"weight":0.30176}]},"recency":{"mean":0.599983,"weightedMean":0.599983,"std_dev":0.304626,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"EPA CTX / IRIS","year":2021,"value":0.368,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":0.368,"weight":0.30176}]},"methodology":{"mean":0.889882,"weightedMean":0.889882,"std_dev":0.144601,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"EPA CTX / IRIS","year":2021,"value":1,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":1,"weight":0.30176}]},"specificity":{"mean":0.8124,"weightedMean":0.8124,"std_dev":0.081941,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"EPA CTX / IRIS","year":2021,"value":0.75,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":0.75,"weight":0.30176}]},"consensus":{"exists":false,"strength":0.294573,"disagreement_magnitude":0.363517,"warning":null}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. EPA CTX / IRIS classifies as higher risk (50th percentile), while EPA CTX / IARC concludes lower risk (25th percentile).","confidence_note":"Moderate-quality evidence base. Disagreement reflects methodological and interpretive differences, not data quality issues.","context_note":null,"warning":null},"sources":[{"id":"iarc_thm_v52_1991","type":"regulatory","title":"IARC Monographs Volume 52: Chlorinated Drinking-water; Chlorination By-products; Some Other Halogenated Compounds — Chlorodibromomethane (DBCM) Group 3, Bromoform Group 3, Chloroform Group 2B, Bromodichloromethane (BDCM) Group 2B (1991)","year":1991},{"id":"epa_stage2_dbpr_2006","type":"regulatory","title":"US EPA: Stage 2 Disinfectants and Disinfection Byproducts Rule (40 CFR Parts 141 and 142) — TTHM MCL 80 μg/L, HAA5 MCL 60 μg/L, Locational Running Annual Average, BDCM Cancer Risk Assessment, Bladder Cancer Epidemiology (2006)","year":2006}],"sources_scope":"context","warnings":["year_inferred:EPA CTX / IRIS:2021","year_inferred:EPA CTX / IARC:2021","unmapped_classification:EPA CTX / CalEPA:chlorodibromomethane (dibromochloromethane) — deli","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 9 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 9 positive"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":3,"db_version":47,"warnings":["year_inferred:EPA CTX / IRIS:2021","year_inferred:EPA CTX / IARC:2021","unmapped_classification:EPA CTX / CalEPA:chlorodibromomethane (dibromochloromethane) — deli","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 9 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 9 positive"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","exposure_ingestion","human_teen","human_elderly","human_infant","human_pregnant"]}