{"hq_id":"hq-c-org-000223","name":"Decabromodiphenyl ether (DecaBDE / BDE-209)","context":"human_adult","timestamp":"2026-08-28T02:48:51.727Z","risk_level":"moderate","risk_profile":{"magnitude":{"mean":0.34747,"weightedMean":0.34747,"std_dev":0.105814,"confidence_interval_95":[0.3,0.5],"source_positions":[{"source":"EPA CTX / IRIS","year":2021,"value":0.5,"weight":0.30176},{"source":"HQ_DIRECT","year":2026,"value":0.3,"weight":0.35},{"source":"EPA CTX / IARC","year":2021,"value":0.25,"weight":0.30176}]},"confidence":{"mean":0.70254,"weightedMean":0.70254,"std_dev":0.154241,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"EPA CTX / IRIS","year":2021,"value":0.82,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":0.82,"weight":0.30176}]},"recency":{"mean":0.599983,"weightedMean":0.599983,"std_dev":0.304626,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"EPA CTX / IRIS","year":2021,"value":0.368,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":0.368,"weight":0.30176}]},"methodology":{"mean":0.889882,"weightedMean":0.889882,"std_dev":0.144601,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"EPA CTX / IRIS","year":2021,"value":1,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":1,"weight":0.30176}]},"specificity":{"mean":0.8124,"weightedMean":0.8124,"std_dev":0.081941,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"EPA CTX / IRIS","year":2021,"value":0.75,"weight":0.30176},{"source":"EPA CTX / IARC","year":2021,"value":0.75,"weight":0.30176}]},"consensus":{"exists":false,"strength":0.294573,"disagreement_magnitude":0.363517,"warning":null}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. EPA CTX / IRIS classifies as higher risk (50th percentile), while EPA CTX / IARC concludes lower risk (25th percentile).","confidence_note":"Moderate-quality evidence base. Disagreement reflects methodological and interpretive differences, not data quality issues.","context_note":null,"warning":null},"sources":[{"id":"stockholm_decabde_2017","type":"regulatory","title":"Stockholm Convention: Decabromodiphenyl Ether (DecaBDE) Listed under Annex A (Elimination), COP-8 Decision SC-8/12, Debromination Concern, Arctic Contamination, RoHS Interaction, Aircraft Exemptions (2017)","year":2017},{"id":"eu_rohs_decabde","type":"regulatory","title":"EU Directive 2011/65/EU (RoHS Recast): DecaBDE Restricted in EEE; DecaBDE REACH SVHC Identification; Debromination Products BDE-47/BDE-99 Metabolite Pathway in Humans and Wildlife (2011)","year":2011}],"sources_scope":"context","warnings":["year_inferred:EPA CTX / IRIS:2021","year_inferred:EPA CTX / IARC:2021","unmapped_classification:UNEP:persistent organic pollutant (pop)","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: negative, 1 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: negative, 1 positive","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: category 2b (score: moderate)","unmapped_classification:EPA CTX / Skin-Eye:skin irritation: category 3 (score: moderate)","unmapped_classification:EPA CTX / Skin-Eye:skin sensitization: not classified (score: low)","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: in vivo: studies indicate no signi"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":3,"db_version":49,"warnings":["year_inferred:EPA CTX / IRIS:2021","year_inferred:EPA CTX / IARC:2021","unmapped_classification:UNEP:persistent organic pollutant (pop)","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: negative, 1 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: negative, 1 positive","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: category 2b (score: moderate)","unmapped_classification:EPA CTX / Skin-Eye:skin irritation: category 3 (score: moderate)","unmapped_classification:EPA CTX / Skin-Eye:skin sensitization: not classified (score: low)","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: in vivo: studies indicate no signi"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant","exposure_dermal","exposure_inhalation","exposure_ingestion","exposure_ocular","occupational_exposure"]}