{"hq_id":"hq-c-org-000198","name":"Heroin (diacetylmorphine)","context":"human_adult","timestamp":"2026-09-10T09:46:09.384Z","risk_level":"extreme","risk_profile":{"magnitude":{"mean":0.925,"weightedMean":0.925,"std_dev":0,"confidence_interval_95":[0.925,0.925],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.925,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates high risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"dea_heroin_schedule_i","type":"regulatory","title":"US DEA: Heroin (Diacetylmorphine) — Schedule I Classification, No Accepted Medical Use, Fentanyl Contamination of Supply Chain, Naloxone Reversal, and Body Packer Toxicology (21 USC 812; 2022)","year":2022},{"id":"cdc_opioid_overdose_surveillance","type":"regulatory","title":"US CDC: Opioid Overdose Surveillance — Heroin-Involved Deaths, NOWS Birth Prevalence, Fentanyl Displacement of Heroin Supply (2013–2023), and Naloxone Distribution Data (2023)","year":2023}],"sources_scope":"context","warnings":["unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (single report) (ames: none","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (single report) (ames: none","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":45,"warnings":["unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (single report) (ames: none","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (single report) (ames: none"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","exposure_ingestion","human_teen","human_elderly","human_infant","human_pregnant","exposure_dermal","exposure_inhalation","exposure_ocular","occupational_exposure"]}