{"hq_id":"hq-c-org-000191","name":"Tartrazine (FD&C Yellow No. 5)","context":"human_adult","timestamp":"2026-08-28T02:41:06.479Z","risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"fda_tartrazine_certified_color","type":"regulatory","title":"US FDA: Tartrazine (FD&C Yellow No. 5) — Certified Color Status, Mandatory Declaration Requirement, Hypersensitivity Cross-Reactivity, and 2011 Food Advisory Committee Review of Hyperactivity Evidence (2022)","year":2022},{"id":"efsa_artificial_colors_hyperactivity_2009","type":"regulatory","title":"EFSA Panel on Food Additives: Re-evaluation of Six Artificial Food Colors and Hyperactivity in Children — Southampton Study Review, Tartrazine (E102), EU Warning Label Requirement, and ADI Confirmation (EFSA Journal 2009;7(11):1351)","year":2009}],"sources_scope":"context","warnings":["unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 30 positiv","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 30 positiv","unmapped_classification:EPA CTX / Skin-Eye:skin sensitisation: in vivo (llna): not likely to ","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":40,"warnings":["unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 30 positiv","unmapped_classification:EPA CTX / Genetox:genotoxicity: positive (ames: positive, 30 positiv","unmapped_classification:EPA CTX / Skin-Eye:skin sensitisation: in vivo (llna): not likely to "]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","exposure_ingestion","human_teen","human_elderly","human_infant","human_pregnant"]}