{"hq_id":"hq-c-org-000154","name":"Temephos","context":"human_adult","timestamp":"2026-10-27T18:02:14.660Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000154","sha256":"a1bab7e2d3115c7b9e2f17a63d36f94a3429c98d80c68aee3d7551702c45f529"}]},"risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"epa_temephos_registration","type":"regulatory","title":"US EPA: Temephos Registration Eligibility Decision — WHO Class U, Drinking Water Use, Mosquito Larval Control, and Ecological Risk (2000)","year":2000},{"id":"who_temephos_specs","type":"regulatory","title":"WHO: Temephos — Specifications for Public Health Pesticides, Drinking Water Guideline, ADI, Onchocerciasis Control Programme Ecological Monitoring (2004)","year":2004},{"id":"r60-2026-09-24-d867-ecfr-29cfr1910.1000","type":"regulatory","title":"§ 1910.1000 Air contaminants.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-22/title-29.xml?part=1910&section=1910.1000"},{"id":"r60-2026-09-29-d899-s4-b07x-who-pesticide-hazard-classification-2019-pdftotext","type":"regulatory","title":"The WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2019","url":"https://iris.who.int/server/api/core/bitstreams/36c193cd-2362-46d1-be00-fef570d80037/content"},{"id":"r60-2026-09-27-d899-who-gdwq-4th-ed-addenda-2026-pdftotext","type":"regulatory","title":"Guidelines for drinking-water quality: fourth edition incorporating the first, second and third addenda","url":"https://iris.who.int/server/api/core/bitstreams/c60cc28e-defe-45ed-b157-71fdd43902bf/content"},{"id":"r60-2026-09-28-d899-s4-b02-who-temephos-background-document-2009-pdftotext","type":"regulatory","title":"Temephos in Drinking-water: Use for Vector Control in Drinking-water Sources and Containers","url":"https://www.who.int/docs/default-source/wash-documents/wash-chemicals/temephos-background-document.pdf?sfvrsn=c34fda71_4"},{"id":"r60-2026-09-28-d449-nepis-200007UJ-ocr-vision","type":"regulatory","title":"RED for Temephos, EPA 738-R-00-020, Jul 2001 (NEPIS 200007UJ)","url":"https://nepis.epa.gov/Exe/ZyPDF.cgi/200007UJ.PDF?Dockey=200007UJ.PDF"},{"id":"src_pubchem_tox_5392","type":"pubchem","title":"PubChem: Toxicity section (CID 5392)","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/5392/JSON?heading=Toxicity"},{"id":"r60-2026-10-03-d923-niosh-npgd0589","type":"regulatory","title":"NIOSH Pocket Guide to Chemical Hazards - Temephos","url":"https://www.cdc.gov/niosh/npg/npgd0589.html"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"pubchem-exp-hazardous-substances-data-bank-cid-5392","type":"database","title":"Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 5392; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/5392/JSON?heading=Experimental+Properties"},{"id":"ctx_pred_dtxsid1032484","type":"reference","title":"EPA CompTox CTX API: predicted properties for DTXSID1032484 (Temephos)","url":"https://comptox.epa.gov/ctx-api/chemical/property/predicted/search/by-dtxsid/DTXSID1032484"}],"sources_scope":"context","derived_markers":[],"warnings":["unmapped_classification:EPA CTX / EPA OPP:not classified as a carcinogen (epa, 2001)","unmapped_classification:Japan, as recorded by ToxValDB:eye irritation: category 2b (score: moderate)","unmapped_classification:Japan, as recorded by ToxValDB:skin irritation: category 3 (score: moderate)","unmapped_classification:Japan, as recorded by ToxValDB:skin sensitization: not classified (score: low)","unmapped_classification:New Zealand, as recorded by ToxValDB:eye irritation: category 6.4a (category 2a) (score","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":48,"warnings":["unmapped_classification:EPA CTX / EPA OPP:not classified as a carcinogen (epa, 2001)","unmapped_classification:Japan, as recorded by ToxValDB:eye irritation: category 2b (score: moderate)","unmapped_classification:Japan, as recorded by ToxValDB:skin irritation: category 3 (score: moderate)","unmapped_classification:Japan, as recorded by ToxValDB:skin sensitization: not classified (score: low)","unmapped_classification:New Zealand, as recorded by ToxValDB:eye irritation: category 6.4a (category 2a) (score"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","exposure_ingestion","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant"]}