{"hq_id":"hq-c-org-000152","name":"Fonofos","context":"human_adult","timestamp":"2026-10-28T19:06:07.996Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"04299bbd676bc92d0c102bae2005f007c261b8ed","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"5feba6939b7e14ce7bc7b932c365e48d8a2cc4db6f0796f4e2a8f8f11126f719","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000152","sha256":"36da335976f2f966476d7acf768d75f86fcf60826dc68bc5cc7620c090727db5"}]},"risk_level":"high","risk_profile":{"magnitude":{"mean":0.625,"weightedMean":0.625,"std_dev":0,"confidence_interval_95":[0.625,0.625],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.625,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates high risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"epa_fonofos_registration","type":"regulatory","title":"US EPA: Fonofos Reregistration Eligibility Decision — Group 2B Carcinogenicity, Dietary and Occupational Risk, Groundwater Contamination, and Cancellation (2001)","year":2001,"check":{"status":"not-checked","notes":"title-only: no url, no source_ref, no capture on file"}},{"id":"src_pubchem_tox_13676","type":"pubchem","title":"PubChem: Toxicity section (CID 13676)","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/13676/JSON?heading=Toxicity"},{"id":"r60-2026-10-03-d923-niosh-npgd0292","type":"regulatory","title":"NIOSH Pocket Guide to Chemical Hazards - Fonofos","url":"https://www.cdc.gov/niosh/npg/npgd0292.html"},{"id":"r60-2026-10-08-d974-tedx-list-full-export","type":"reference_database","title":"TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018)","url":"https://endocrinedisruption.org/interactive-tools/tedx-list-of-potential-endocrine-disruptors/search-the-tedx-list"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"pubchem-exp-cameo-chemicals-cid-13676","type":"database","title":"CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 13676; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/13676/JSON?heading=Experimental+Properties"},{"id":"pubchem-exp-ilo-who-international-chemical-safety-ca-cid-13676","type":"database","title":"ILO-WHO International Chemical Safety Cards (ICSCs), as recorded by PubChem (Experimental Properties, CID 13676; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/13676/JSON?heading=Experimental+Properties"},{"id":"ctx_pred_dtxsid2024113","type":"reference","title":"EPA CompTox CTX API: predicted properties for DTXSID2024113 (Fonofos)","url":"https://comptox.epa.gov/ctx-api/chemical/property/predicted/search/by-dtxsid/DTXSID2024113"},{"id":"r60-2026-10-01-echa-annex-vi-clp-table-atp23-xlsx","type":"regulatory","title":"ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP)","url":"https://echa.europa.eu/documents/10162/17218/annex_vi_clp_table_atp23_en.xlsx/b3816c13-81a3-816d-773a-62e88c4e2700?t=1761727004499"},{"id":"r60-2026-09-30-d907-5aeeb65f25","type":"regulatory","title":"US EPA Office of Pesticide Programs: Chemicals Evaluated for Carcinogenic Potential, 2024 edition (NPIC-hosted copy)","year":2024,"url":"http://npic.orst.edu/chemicals_evaluated.pdf"}],"sources_scope":"context","derived_markers":[],"warnings":["unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: negativ","unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: negativ","unmapped_classification:Japan, as recorded by ToxValDB:skin irritation: not classified (score: low)","aggravating_only:negative_carcinogenicity_dropped:EPA CTX / EPA OPP:human_adult","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":50,"warnings":["unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: negativ","unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: negativ","unmapped_classification:Japan, as recorded by ToxValDB:skin irritation: not classified (score: low)","aggravating_only:negative_carcinogenicity_dropped:EPA CTX / EPA OPP:human_adult"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","exposure_dermal","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant","agricultural_worker"]}