{"hq_id":"hq-c-org-000122","name":"PFHxS (Perfluorohexane sulfonic acid)","context":"human_adult","timestamp":"2026-05-01T18:32:30.696Z","risk_level":"high","risk_profile":{"magnitude":{"mean":0.687559,"weightedMean":0.687559,"std_dev":0.29764,"confidence_interval_95":[0.95,0.95],"source_positions":[{"source":"IARC","year":2023,"value":0.95,"weight":0.45018},{"source":"HQ_DIRECT","year":2026,"value":0.35,"weight":0.35}]},"confidence":{"mean":0.680031,"weightedMean":0.680031,"std_dev":0.158741,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"IARC","year":2023,"value":0.82,"weight":0.45018}]},"recency":{"mean":0.746268,"weightedMean":0.746268,"std_dev":0.223726,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"IARC","year":2023,"value":0.549,"weight":0.45018}]},"methodology":{"mean":0.86878,"weightedMean":0.86878,"std_dev":0.14882,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"IARC","year":2023,"value":1,"weight":0.45018}]},"specificity":{"mean":0.824358,"weightedMean":0.824358,"std_dev":0.084331,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"IARC","year":2023,"value":0.75,"weight":0.45018}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0.396157,"warning":"limited_synthesis"}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. IARC classifies as higher risk (95th percentile), while HQ_DIRECT concludes lower risk (35th percentile).","confidence_note":"Moderate-quality evidence base.","context_note":null,"warning":"limited_synthesis"},"sources":[],"warnings":["limited_synthesis"],"meta":{"synthesis_version":"1.0.0","config_version":"1.0.0","n_sources":2,"db_version":42},"schema":"synthesis"}