{"hq_id":"hq-c-org-000095","name":"Camphor","context":"human_adult","timestamp":"2026-10-27T20:54:32.265Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-org-000095","sha256":"788261d64c8f2116bdd7eba50d14dbf4b87b5df684cb30e51fb4dc58f9df06bc"}]},"risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"fda_camphor_reg","type":"regulatory","title":"US FDA: Camphor — OTC External Analgesic Drug Products; Final Monograph (21 CFR 348) and Camphorated Oil Ban (>11%)","year":1983},{"id":"aspca_apcc_camphor","type":"veterinary","title":"ASPCA Animal Poison Control Center: Camphor Toxicosis in Dogs and Cats — Clinical Presentation, Management, and Product Sources","year":2022},{"id":"r60-2026-09-28-d899-s4-b02-ecfr-21cfr310.502","type":"regulatory","title":"§ 310.502 Certain drugs accorded new drug status through rulemaking procedures.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-24/title-21.xml?part=310&section=310.502"},{"id":"r60-2026-09-28-d899-s4-b02-fda-rulemaking-history-otc-camphorated-oil","type":"regulatory","title":"Rulemaking History for OTC Camphorated Oil Drug Products | FDA","url":"https://www.fda.gov/drugs/historical-status-otc-rulemakings/rulemaking-history-otc-camphorated-oil-drug-products"},{"id":"r60-2026-09-27-d899-s4-fda-otc-monograph-m017-external-analgesic-2023-pdftotext","type":"regulatory","title":"Over-the-Counter (OTC) Monograph M017: External Analgesic Drug Products for Over-the-Counter Human Use","url":"https://www.accessdata.fda.gov/drugsatfda_docs/omuf/monographs/OTC%20Monograph_M017-External%20Analgesic%20Drug%20Products%20for%20OTC%20Human%20Use%2005.02.2023.pdf"},{"id":"echa-chem-reach-registrations","type":"regulatory","title":"ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances)","year":2026,"url":"https://chem.echa.europa.eu/"},{"id":"src_pubchem_tox_2537","type":"pubchem","title":"PubChem: Toxicity section (CID 2537)","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/2537/JSON?heading=Toxicity"},{"id":"r60-2026-09-27-d820-osha-annotated-table-z-1","type":"regulatory","title":"Permissible Exposure Limits – OSHA Annotated Table Z-1","url":"https://www.osha.gov/annotated-pels/table-z-1"},{"id":"r60-2026-09-28-d899-s4-b02-govinfo-fr-1982-09-21-pdftotext","type":"regulatory","title":"Federal Register, Vol. 47, No. 183, Tuesday, September 21, 1982 (whole issue)","url":"https://www.govinfo.gov/content/pkg/FR-1982-09-21/pdf/FR-1982-09-21.pdf"},{"id":"r60-2026-09-24-d867-ecfr-29cfr1910.1000","type":"regulatory","title":"29 CFR 1910.1000 Air contaminants (Tables Z-1, Z-2, Z-3) — eCFR full-text XML, 2026-09-22","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-22/title-29.xml?part=1910&section=1910.1000"},{"id":"r60-2026-09-26-d867-cc1-eurlex-cellar-02009R1223-20260518","type":"regulatory","title":"Consolidated TEXT: 32009R1223 — EN — 18.05.2026 (Regulation (EC) No 1223/2009, cosmetic products)","url":"https://publications.europa.eu/resource/celex/02009R1223-20260518"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"ctx_pred_dtxsid5030955","type":"reference","title":"EPA CompTox CTX API: predicted properties for DTXSID5030955 (Camphor)","url":"https://comptox.epa.gov/ctx-api/chemical/property/predicted/search/by-dtxsid/DTXSID5030955"}],"sources_scope":"context","derived_markers":[],"warnings":["unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: positiv","unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: positiv","unmapped_classification:Japan, as recorded by ToxValDB:eye irritation: category 2b (score: moderate)","unmapped_classification:New Zealand, as recorded by ToxValDB:eye irritation: category 6.4a (category 2a) (score","unmapped_classification:New Zealand, as recorded by ToxValDB:skin irritation: category 6.3b (category 3) (score","unmapped_classification:New Zealand, as recorded by ToxValDB:skin sensitization: category 6.5b (category 1) (sc","unmapped_classification:ECHA eChemPortal, as recorded by ToxValDB:skin sensitisation: in vivo (non-llna): not likely","unmapped_classification:ECHA eChemPortal, as recorded by ToxValDB:eye irritation: in vivo: studies indicate no signi","unmapped_classification:ECHA eChemPortal, as recorded by ToxValDB:skin irritation: in vivo: studies indicate no sign","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":50,"warnings":["unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: positiv","unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: positiv","unmapped_classification:Japan, as recorded by ToxValDB:eye irritation: category 2b (score: moderate)","unmapped_classification:New Zealand, as recorded by ToxValDB:eye irritation: category 6.4a (category 2a) (score","unmapped_classification:New Zealand, as recorded by ToxValDB:skin irritation: category 6.3b (category 3) (score","unmapped_classification:New Zealand, as recorded by ToxValDB:skin sensitization: category 6.5b (category 1) (sc","unmapped_classification:ECHA eChemPortal, as recorded by ToxValDB:skin sensitisation: in vivo (non-llna): not likely","unmapped_classification:ECHA eChemPortal, as recorded by ToxValDB:eye irritation: in vivo: studies indicate no signi","unmapped_classification:ECHA eChemPortal, as recorded by ToxValDB:skin irritation: in vivo: studies indicate no sign"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["dog","cat","human_adult","human_child","exposure_ingestion","exposure_dermal","human_teen","human_elderly","human_infant","human_pregnant"]}