{"hq_id":"hq-c-org-000006","name":"Bisphenol A","context":"human_adult","risk_level":"conflicted","schema":"legacy","note":"Synthesis unavailable: compound lacks vectorizable regulatory classifications. Raw safety data returned.","data":{"risk_level":"conflicted","summary":"Major regulatory disagreement. EFSA (2023): Current dietary exposure exceeds safe levels by 100-1000x. FDA: Safe at current levels. Academic consensus increasingly supports concern.","exposure_routes":{"dietary":"Primary route. Migration from food packaging, especially canned foods and polycarbonate containers. Increased by heat, acidic/basic pH.","dermal":"Thermal paper (receipts) is significant source. Absorption through skin.","inhalation":"Dust and air in some environments"},"health_effects_reported":["Reproductive effects (reduced fertility, altered hormone levels)","Metabolic effects (obesity, diabetes association)","Neurological effects","Immune system effects (basis of EFSA 2023 TDI)","Possible carcinogenicity (hormone-related cancers)","Chemotherapy resistance (emerging concern)"],"biomonitoring":"Detected in majority of humans tested - urine, blood, breast milk, placenta","source_refs":["efsa_2023","vandenberg_2021","pmc_cancer_review","r60-2026-10-01-echa-annex-vi-clp-table-atp23-xlsx","echa-chem-reach-registrations","r60-2026-09-25-d897-eu-cellar-02004L0037-20240408","r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","r60-2026-10-02-d968-echa-candidate-list-xml","pubchem-exp-hazardous-substances-data-bank-cid-6623","pubchem-exp-cameo-chemicals-cid-6623","src_pubchem_tox_6623","ctx_pred_dtxsid7020182"]},"meta":{"synthesis_version":"n/a","timestamp":"2026-10-28T20:03:02.758Z"},"_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","human_pregnant","dog","cat","human_teen","human_elderly","human_infant","exposure_dermal","exposure_inhalation","exposure_ingestion","exposure_ocular","occupational_exposure"]}