{"hq_id":"hq-c-org-000001","name":"Glyphosate","context":"human_adult","timestamp":"2026-04-25T19:16:27.275Z","risk_level":"moderate","risk_profile":{"magnitude":{"mean":0.34481,"weightedMean":0.34481,"std_dev":0.222801,"confidence_interval_95":[0.18,0.7],"source_positions":[{"source":"IARC","year":2015,"value":0.7,"weight":0.41},{"source":"HQ_DIRECT","year":2026,"value":0.35,"weight":0.35},{"source":"EFSA","year":2015,"value":0.18,"weight":0.41},{"source":"US EPA","year":2020,"value":0.15,"weight":0.41}]},"confidence":{"mean":0.749114,"weightedMean":0.749114,"std_dev":0.132886,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"IARC","year":2015,"value":0.82,"weight":0.41},{"source":"US EPA","year":2020,"value":0.82,"weight":0.41},{"source":"EFSA","year":2015,"value":0.82,"weight":0.41}]},"recency":{"mean":0.610759,"weightedMean":0.610759,"std_dev":0.207634,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"IARC","year":2015,"value":0.5,"weight":0.41},{"source":"US EPA","year":2020,"value":0.5,"weight":0.41},{"source":"EFSA","year":2015,"value":0.5,"weight":0.41}]},"methodology":{"mean":0.933544,"weightedMean":0.933544,"std_dev":0.124581,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"IARC","year":2015,"value":1,"weight":0.41},{"source":"US EPA","year":2020,"value":1,"weight":0.41},{"source":"EFSA","year":2015,"value":1,"weight":0.41}]},"specificity":{"mean":0.787658,"weightedMean":0.787658,"std_dev":0.070596,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"IARC","year":2015,"value":0.75,"weight":0.41},{"source":"US EPA","year":2020,"value":0.75,"weight":0.41},{"source":"EFSA","year":2015,"value":0.75,"weight":0.41}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0.344616,"warning":null}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. IARC classifies as higher risk (70th percentile), while US EPA concludes lower risk (15th percentile).","confidence_note":"Moderate-quality evidence base. Disagreement reflects methodological and interpretive differences, not data quality issues.","context_note":null,"warning":null},"sources":[],"warnings":["Failed to vectorize source EPA CTX / CalEPA: Source must have year field","unmapped_classification:EPA CTX / IRIS:d (not classifiable as to human carcinogenicity)","unmapped_classification:EPA CTX / IARC:group 2a - probably carcinogenic to humans","unmapped_classification:EPA CTX / EPA OPP:group e evidence of non-carcinogenicity for humans","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 0 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 0 positive","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: eye dam. 1 (score: very high)","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: category 1 (score: very high)","unmapped_classification:EPA CTX / Skin-Eye:skin irritation: not classified (score: low)","unmapped_classification:EPA CTX / Skin-Eye:skin sensitization: not classified (score: low)","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: category 6.4a (category 2a) (score","unmapped_classification:IARC:group_2a","unmapped_classification:US_EPA:not_likely_carcinogen","unmapped_classification:EU_REACH:approved_renewed","unmapped_classification:PROP_65:carcinogen"],"meta":{"synthesis_version":"1.0.0","config_version":"1.0.0","n_sources":4,"db_version":45,"warnings":["Failed to vectorize source EPA CTX / CalEPA: Source must have year field","unmapped_classification:EPA CTX / IRIS:d (not classifiable as to human carcinogenicity)","unmapped_classification:EPA CTX / IARC:group 2a - probably carcinogenic to humans","unmapped_classification:EPA CTX / EPA OPP:group e evidence of non-carcinogenicity for humans","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 0 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 0 positive","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: eye dam. 1 (score: very high)","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: category 1 (score: very high)","unmapped_classification:EPA CTX / Skin-Eye:skin irritation: not classified (score: low)","unmapped_classification:EPA CTX / Skin-Eye:skin sensitization: not classified (score: low)","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: category 6.4a (category 2a) (score","unmapped_classification:IARC:group_2a","unmapped_classification:US_EPA:not_likely_carcinogen","unmapped_classification:EU_REACH:approved_renewed","unmapped_classification:PROP_65:carcinogen"]},"schema":"synthesis"}