{"hq_id":"hq-c-mix-000082","name":"Cladosporium","context":"human_adult","risk_level":"moderate","schema":"legacy","note":"Synthesis unavailable: compound lacks vectorizable regulatory classifications. Raw safety data returned.","data":{"risk_level":"moderate","summary":"Cladosporium is the most common airborne mold genus globally, with C. cladosporioides, C. herbarum, and C. sphaerospermum being the dominant species. Outdoor concentrations peak in summer/autumn at 10,000-50,000 spores/m3 in temperate climates. Dark olive-green to brown colonies with velvety texture; spores are characteristically shield-shaped (scutuloconidium) and pigmented (melanized). Primary health significance is allergenic rather than infectious or toxicogenic. Cladosporium allergens (Cla h 1-12) are among the most common aeroallergen sensitizers: 10-60% of allergic individuals show positive skin prick tests to Cladosporium extracts. Strong epidemiological association with allergic rhinitis and asthma exacerbation. IgE cross-reactivity with Alternaria allergens is documented. Cladosporium is an uncommon cause of infection (chromoblastomycosis, keratitis, brain abscess) primarily in immunocompromised patients — extremely rare in immunocompetent hosts. Indoor presence: commonly found on window frames, shower curtains, HVAC coils, and any damp surface. Does not require as much water as Stachybotrys — can grow at water activity as low as 0.85.","source_refs":["aletheia_fungi_batch_2026"]},"meta":{"synthesis_version":"n/a","timestamp":"2026-05-01T14:23:20.634Z"}}