{"hq_id":"hq-c-mix-000068","name":"Diesel exhaust particulate (DEP)","context":"human_adult","timestamp":"2026-06-17T21:59:58.043Z","risk_level":"severe","risk_profile":{"magnitude":{"mean":0.748259,"weightedMean":0.748259,"std_dev":0.128191,"confidence_interval_95":[0.65,0.95],"source_positions":[{"source":"IARC","year":2021,"value":0.95,"weight":0.41},{"source":"EPA","year":2021,"value":0.75,"weight":0.41},{"source":"NTP","year":2021,"value":0.65,"weight":0.41},{"source":"HQ_DIRECT","year":2026,"value":0.625,"weight":0.35}]},"confidence":{"mean":0.749114,"weightedMean":0.749114,"std_dev":0.132886,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"IARC","year":2021,"value":0.82,"weight":0.41},{"source":"NTP","year":2021,"value":0.82,"weight":0.41},{"source":"EPA","year":2021,"value":0.82,"weight":0.41}]},"recency":{"mean":0.610759,"weightedMean":0.610759,"std_dev":0.207634,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"IARC","year":2021,"value":0.5,"weight":0.41},{"source":"NTP","year":2021,"value":0.5,"weight":0.41},{"source":"EPA","year":2021,"value":0.5,"weight":0.41}]},"methodology":{"mean":0.933544,"weightedMean":0.933544,"std_dev":0.124581,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"IARC","year":2021,"value":1,"weight":0.41},{"source":"NTP","year":2021,"value":1,"weight":0.41},{"source":"EPA","year":2021,"value":1,"weight":0.41}]},"specificity":{"mean":0.787658,"weightedMean":0.787658,"std_dev":0.070596,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"IARC","year":2021,"value":0.75,"weight":0.41},{"source":"NTP","year":2021,"value":0.75,"weight":0.41},{"source":"EPA","year":2021,"value":0.75,"weight":0.41}]},"consensus":{"exists":false,"strength":0.145393,"disagreement_magnitude":0.339684,"warning":null}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. IARC classifies as higher risk (95th percentile), while HQ_DIRECT concludes lower risk (63th percentile).","confidence_note":"Moderate-quality evidence base. Disagreement reflects methodological and interpretive differences, not data quality issues.","context_note":null,"warning":null},"sources":[],"warnings":["year_inferred:IARC:2021","year_inferred:NTP:2021","year_inferred:EPA:2021","unmapped_classification:CARB:toxic air contaminant (tac). diesel risk reduction","unmapped_classification:EU:emep/eea air pollutant inventories. euro vi emissi"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":4,"db_version":3,"warnings":["year_inferred:IARC:2021","year_inferred:NTP:2021","year_inferred:EPA:2021","unmapped_classification:CARB:toxic air contaminant (tac). diesel risk reduction","unmapped_classification:EU:emep/eea air pollutant inventories. euro vi emissi"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer"}