{"hq_id":"hq-c-mix-000045","name":"Diesel Exhaust Particulate (Complex Mixture)","context":"human_adult","timestamp":"2026-10-27T20:59:44.990Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-mix-000045","sha256":"08ab94959dbc550f3a37d6ff5a8aca53f64f56ebbea50c1fbc9e373d779d4205"}]},"risk_level":"extreme","risk_profile":{"magnitude":{"mean":0.95,"weightedMean":0.95,"std_dev":0,"confidence_interval_95":[0.95,0.95],"source_positions":[{"source":"IARC","year":2014,"value":0.95,"weight":0.41}]},"confidence":{"mean":0.82,"weightedMean":0.82,"std_dev":0,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"IARC","year":2014,"value":0.82,"weight":0.41}]},"recency":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"IARC","year":2014,"value":0.5,"weight":0.41}]},"methodology":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"IARC","year":2014,"value":1,"weight":0.41}]},"specificity":{"mean":0.75,"weightedMean":0.75,"std_dev":0,"confidence_interval_95":[0.75,0.75],"source_positions":[{"source":"IARC","year":2014,"value":0.75,"weight":0.41}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (IARC, 2014) indicates extreme risk.","confidence_note":"High-quality evidence exists across sources. Disagreement reflects methodological and interpretive differences, not data quality issues.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"src_001","type":"regulatory","title":"IARC Monographs on the Evaluation of Carcinogenic Risk to Humans — Diesel Engine Exhaust (Monograph 105, 2012)","year":2012,"url":"https://www.ncbi.nlm.nih.gov/books/NBK294255/"},{"id":"src_002","type":"regulatory","title":"EPA National Ambient Air Quality Standard (NAAQS) for PM2.5 (2024 Revision: 9 µg/m³ annual average)","year":2024,"url":"https://www.epa.gov/pm-pollution/final-reconsideration-national-ambient-air-quality-standards-particulate-matter-pm"},{"id":"src_003","type":"journal","title":"Children's Health Study (SCAB): Long-Term Lung Function Development in Highway-Adjacent Children; PM2.5 Asthma Incidence 2×","year":2007,"url":"https://pubmed.ncbi.nlm.nih.gov/17307103/"},{"id":"src_004","type":"regulatory","title":"US EPA School Bus Emissions and Diesel Engine Standard (Heavy-Duty Engine Standards; School Bus Electrification IRA 2022)","year":2022,"url":"https://www.epa.gov/cleanschoolbus"},{"id":"r60-2026-09-26-d867-cc2-ecfr-40cfr50.18","type":"regulatory","title":"§ 50.18 National primary ambient air quality standards for PM2.5.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-24/title-40.xml?part=50&section=50.18"},{"id":"r60-2026-09-26-d867-cc2-ecfr-40cfr50.20","type":"regulatory","title":"§ 50.20 National primary ambient air quality standards for PM2.5.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-24/title-40.xml?part=50&section=50.20"},{"id":"r60-iarc-105-diesel-engine-exhaust-group1","type":"regulatory","title":"IARC Monographs Vol 105 §6 Evaluation — Diesel Engine Exhaust (Group 1)","url":"https://www.ncbi.nlm.nih.gov/books/NBK294255/"}],"sources_scope":"record","derived_markers":[],"warnings":["single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":17},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","exposure_inhalation","environmental","human_teen","human_elderly","human_infant","human_pregnant"]}