{"hq_id":"hq-c-mix-000035","name":"Coal Dust","context":"human_adult","timestamp":"2026-08-28T04:03:32.555Z","risk_level":"moderate_to_high","risk_profile":{"magnitude":{"mean":0.422697,"weightedMean":0.422697,"std_dev":0.186915,"confidence_interval_95":[0.625,0.625],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.625,"weight":0.35},{"source":"IARC","year":1997,"value":0.25,"weight":0.41}]},"confidence":{"mean":0.672632,"weightedMean":0.672632,"std_dev":0.159501,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"IARC","year":1997,"value":0.82,"weight":0.41}]},"recency":{"mean":0.730263,"weightedMean":0.730263,"std_dev":0.24922,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"IARC","year":1997,"value":0.5,"weight":0.41}]},"methodology":{"mean":0.861842,"weightedMean":0.861842,"std_dev":0.149532,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"IARC","year":1997,"value":1,"weight":0.41}]},"specificity":{"mean":0.828289,"weightedMean":0.828289,"std_dev":0.084735,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"IARC","year":1997,"value":0.75,"weight":0.41}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0.349836,"warning":"limited_synthesis"}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. HQ_DIRECT classifies as higher risk (63th percentile), while IARC concludes lower risk (25th percentile).","confidence_note":"Moderate-quality evidence base.","context_note":null,"warning":"limited_synthesis"},"sources":[{"id":"iarc_coal_dust_2012","type":"regulatory","title":"IARC Monographs Volume 68 (1997): Coal Dust — Group 3 (not classifiable as to carcinogenicity); Coal Workers' Pneumoconiosis (CWP) / Progressive Massive Fibrosis (PMF); NIOSH REL 0.4-1.0 mg/m3; post-2012 CWP resurgence; crystalline-silica co-exposure","year":2012,"url":"https://inchem.org/documents/iarc/vol68/coal.html"},{"id":"niosh_coal_dust_pocket_guide","type":"regulatory","title":"NIOSH Pocket Guide to Chemical Hazards — Coal Dust (Bituminous + Anthracite; REL 0.9 mg/m³ TWA respirable; 'Ca' carcinogen designation; CWP + black-lung cohort framework)","year":2019},{"id":"msha_respirable_coal_dust_pel","type":"regulatory","title":"MSHA 30 CFR 70 + 90 — Respirable Coal Mine Dust Standard (1.5 mg/m³ TWA underground + surface mines as of August 2016; CWP-eligibility-monitoring framework + Coal Workers' X-Ray Surveillance Program)","year":2016},{"id":"attfield_coal_miner_lung_cancer_2012","type":"study","title":"Attfield MD, Schleiff PL, Lubin JH et al. — The Diesel Exhaust in Miners Study cohort framework + coal-miner lung-cancer signal (NCI/NIOSH joint-cohort framework)","year":2012}],"sources_scope":"record","warnings":["limited_synthesis"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":2,"db_version":13},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant","exposure_dermal","exposure_inhalation","exposure_ingestion","exposure_ocular","occupational_exposure"]}