{"hq_id":"hq-c-ino-000110","name":"Stannous fluoride","context":"human_adult","timestamp":"2026-10-27T21:23:41.638Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-ino-000110","sha256":"b3afa5a04cf56b6193258331be963be229a3f63daa53f1944fc6901fc3a35a3e"}]},"risk_level":"high","risk_profile":{"magnitude":{"mean":0.625,"weightedMean":0.625,"std_dev":0,"confidence_interval_95":[0.625,0.625],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.625,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates high risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"src_001","type":"database","title":"PubChem Compound CID 24550","url":"https://pubchem.ncbi.nlm.nih.gov/compound/24550"},{"id":"src_002","type":"epa","title":"EPA CompTox Chemicals Dashboard — DTXSID6064822","url":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID6064822"},{"id":"src_003","type":"reference","title":"ATSDR Toxicological Profile — CAS 7783-47-3","url":"https://www.atsdr.cdc.gov/toxprofiledocs/index.html"},{"id":"r60-2026-09-24-d867-ecfr-29cfr1910.1000","type":"regulatory","title":"§ 1910.1000 Air contaminants.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-22/title-29.xml?part=1910&section=1910.1000"},{"id":"echa-chem-reach-registrations","type":"regulatory","title":"ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances)","year":2026,"url":"https://chem.echa.europa.eu/"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"r60-2026-09-27-d820-osha-annotated-table-z-1","type":"regulatory","title":"Permissible Exposure Limits – OSHA Annotated Table Z-1","url":"https://www.osha.gov/annotated-pels/table-z-1"},{"id":"r60-2026-10-03-d923-niosh-npgd0563","type":"regulatory","title":"NIOSH Pocket Guide to Chemical Hazards - Sodium fluoride (as F)","url":"https://www.cdc.gov/niosh/npg/npgd0563.html"}],"sources_scope":"context","derived_markers":[],"warnings":["unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: positiv","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":40,"warnings":["unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: positiv"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["aquatic_life","cat","dog","exposure_dermal","exposure_ingestion","exposure_ocular","human_adult","human_child","human_teen","human_elderly","human_infant","human_pregnant","exposure_inhalation","occupational_exposure"]}