{"hq_id":"hq-c-ino-000082","name":"Sodium phosphate dibasic (E339ii)","context":"human_adult","timestamp":"2026-10-27T20:02:06.736Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-ino-000082","sha256":"36333b166753c3122744194dc9d0e7c9e1b1e0b4aad1f53e463179e22ce4251a"}]},"risk_level":"low","risk_profile":{"magnitude":{"mean":0.2,"weightedMean":0.2,"std_dev":0,"confidence_interval_95":[0.2,0.2],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.2,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates low risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"disodium_phosphate_e339_efsa2019","type":"regulatory","title":"Sodium Phosphate Dibasic E339ii CAS 10028-24-7 Dihydrate Na2HPO4 MW 141.96; EFSA 2019 Group ADI 40 mg P/kg/day E338-E452 EFSA Journal 2019;17(3):5674; FDA GRAS 21 CFR 182.6290; Processed Cheese Emulsifying Salt Displace Calcium Casein Micelle Homogeneous Melt Slices Spreads; Leavening Alkali Baking Powder; Sequestrant Divalent Metal Chelation; Meat Water Holding Capacity; Inorganic Phosphate 70-100% Absorption vs Natural 40-60% Higher Bioavailability; Clinical Laxative Fleet Phospho-Soda 24-30g Acute Phosphate Nephropathy Hyperphosphatemia QT Prolongation FDA 2008 Safety Communication; WWTP Phosphate Removal Chemical Precipitation Alum Ferric EBPR; Eutrophication Nutrient Loading","year":2019},{"id":"pubchem-computed-cid-6451167","type":"database","title":"PubChem computed properties for CID 6451167 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/6451167"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"r60-2026-10-02-d-955-s9-d955-s9-osha-table-z-1","type":"regulatory","title":"Permissible Exposure Limits – OSHA Annotated Table Z-1","url":"https://www.osha.gov/annotated-pels/table-z-1"},{"id":"pubchem-computed-structure-cid-6451167","type":"database","title":"PubChem computed structure descriptors for CID 6451167 (computed, not measured; as recorded by PubChem)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/6451167"}],"sources_scope":"record","derived_markers":[],"warnings":["unmapped_classification:IARC:not evaluated by iarc for carcinogenicity — sodium","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":36,"warnings":["unmapped_classification:IARC:not evaluated by iarc for carcinogenicity — sodium"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant"]}