{"hq_id":"hq-c-ino-000027","name":"Antimony","context":"human_adult","timestamp":"2026-08-28T04:16:49.805Z","risk_level":"moderate_to_high","risk_profile":{"magnitude":{"mean":0.525039,"weightedMean":0.525039,"std_dev":0.198426,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"IARC","year":2023,"value":0.7,"weight":0.45018},{"source":"HQ_DIRECT","year":2026,"value":0.3,"weight":0.35}]},"confidence":{"mean":0.680031,"weightedMean":0.680031,"std_dev":0.158741,"confidence_interval_95":[0.82,0.82],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35},{"source":"IARC","year":2023,"value":0.82,"weight":0.45018}]},"recency":{"mean":0.746268,"weightedMean":0.746268,"std_dev":0.223726,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35},{"source":"IARC","year":2023,"value":0.549,"weight":0.45018}]},"methodology":{"mean":0.86878,"weightedMean":0.86878,"std_dev":0.14882,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35},{"source":"IARC","year":2023,"value":1,"weight":0.45018}]},"specificity":{"mean":0.824358,"weightedMean":0.824358,"std_dev":0.084331,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35},{"source":"IARC","year":2023,"value":0.75,"weight":0.45018}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0.341965,"warning":"limited_synthesis"}},"interpretation":{"summary":"Regulatory agencies show substantial disagreement. IARC classifies as higher risk (70th percentile), while HQ_DIRECT concludes lower risk (30th percentile).","confidence_note":"Moderate-quality evidence base.","context_note":null,"warning":"limited_synthesis"},"sources":[{"id":"atsdr_antimony_tox","type":"regulatory","title":"ATSDR: Toxicological Profile for Antimony — Trivalent vs Pentavalent Toxicity, Occupational Lung Disease, IARC 2B Context (superseded by Monograph 131), and Flame Retardant Use","year":2019},{"id":"epa_antimony_iris","type":"regulatory","title":"US EPA IRIS: Antimony (III) — Oral Reference Dose, Drinking Water MCL (6 ppb), Blood Cholesterol/Glucose Endpoint, and Inhalation Reference Concentration","year":1992}],"sources_scope":"context","warnings":["unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: category 6.4a (category 2a) (score","unmapped_classification:EPA CTX / Skin-Eye:skin irritation: category 6.3b (category 3) (score","limited_synthesis"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":2,"db_version":47,"warnings":["unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Genetox:genotoxicity: negative (ames: negative, 1 positive","unmapped_classification:EPA CTX / Skin-Eye:eye irritation: category 6.4a (category 2a) (score","unmapped_classification:EPA CTX / Skin-Eye:skin irritation: category 6.3b (category 3) (score"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","exposure_inhalation","human_child","exposure_ingestion","aquatic_life","dog","cat","human_teen","human_elderly","human_infant","human_pregnant","exposure_dermal","exposure_ocular","occupational_exposure"]}