{"hq_id":"hq-c-ino-000013","name":"Ammonia","context":"human_adult","timestamp":"2026-10-27T21:05:40.854Z","derived_by":{"label":"ALETHEIA-derived","engine":{"commit":"a1c6e861599cc34c5db0318ea1a7ac13a327e074","commit_source":"vercel_env","tree_clean":null},"params":{"sha256":"88ae43137e58ed0cd65588409efefee0d90253da01ef4459bf9ee25f888ec9a0","files":["axes.json","context-specificity.json","regulatory-mappings.json","synthesis-params.json","thresholds.json"]},"clock":{"year":2026},"inputs":[{"id":"hq-c-ino-000013","sha256":"fd673decdf1ec5049af9887fc38f5574294d11f5ccf0523cf6e196b44c77c977"}]},"risk_level":"moderate","risk_profile":{"magnitude":{"mean":0.35,"weightedMean":0.35,"std_dev":0,"confidence_interval_95":[0.35,0.35],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.35,"weight":0.35}]},"confidence":{"mean":0.5,"weightedMean":0.5,"std_dev":0,"confidence_interval_95":[0.5,0.5],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.5,"weight":0.35}]},"recency":{"mean":1,"weightedMean":1,"std_dev":0,"confidence_interval_95":[1,1],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":1,"weight":0.35}]},"methodology":{"mean":0.7,"weightedMean":0.7,"std_dev":0,"confidence_interval_95":[0.7,0.7],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.7,"weight":0.35}]},"specificity":{"mean":0.92,"weightedMean":0.92,"std_dev":0,"confidence_interval_95":[0.92,0.92],"source_positions":[{"source":"HQ_DIRECT","year":2026,"value":0.92,"weight":0.35}]},"consensus":{"exists":false,"strength":0,"disagreement_magnitude":0,"warning":"single_source_warning"}},"interpretation":{"summary":"Single source (HQ_DIRECT, 2026) indicates moderate risk.","confidence_note":"Evidence quality varies; interpretation requires caution.","context_note":null,"warning":"single_source_warning"},"sources":[{"id":"atsdr_ammonia","type":"report","title":"ATSDR Toxicological Profile for Ammonia","year":2004},{"id":"epa_ammonia_tox","type":"regulatory","title":"US EPA Ambient Water Quality Criteria for Ammonia (Freshwater)","year":2013},{"id":"niosh_ammonia","type":"regulatory","title":"NIOSH Pocket Guide to Chemical Hazards: Ammonia","year":2019,"url":"https://www.cdc.gov/niosh/npg/npgd0028.html"},{"id":"r60-2026-09-25-d867-niosh-npg-npgd0028","type":"regulatory","title":"CDC - NIOSH Pocket Guide to Chemical Hazards - Ammonia","url":"https://www.cdc.gov/niosh/npg/npgd0028.html"},{"id":"r60-2026-09-24-d867-ecfr-29cfr1910.1000","type":"regulatory","title":"§ 1910.1000 Air contaminants.","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-22/title-29.xml?part=1910&section=1910.1000"},{"id":"r60-2026-09-25-d867-ecfr-29cfr1910.119","type":"regulatory","title":"29 CFR 1910.119, Appendix A (eCFR editorial compilation, as of 2026-09-22)","url":"https://www.ecfr.gov/api/versioner/v1/full/2026-09-22/title-29.xml?part=1910&section=1910.119"},{"id":"r60-2026-10-01-echa-annex-vi-clp-table-atp23-xlsx","type":"regulatory","title":"ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) (secondary: unofficial by its own statement)","url":"https://echa.europa.eu/documents/10162/17218/annex_vi_clp_table_atp23_en.xlsx/b3816c13-81a3-816d-773a-62e88c4e2700?t=1761727004499"},{"id":"echa-chem-reach-registrations","type":"regulatory","title":"ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances)","year":2026,"url":"https://chem.echa.europa.eu/"},{"id":"src_pubchem_tox_222","type":"pubchem","title":"PubChem: Toxicity section (CID 222)","url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/222/JSON?heading=Toxicity"},{"id":"r60-2026-09-30-d907-f1d6179110","type":"regulatory","title":"Industry Code of Practice on Chemicals Classification and Hazard Communication (DOSH Malaysia)","url":"https://dosh.gov.my/wp-content/uploads/2026/06/ICOP-Chemical-Classification-and-Hazard-Communication-2014.pdf"},{"id":"r60-2026-09-25-d897-eu-cellar-02000L0039-20210520","type":"regulatory","title":"Consolidated TEXT: 32000L0039 — EN — 20.05.2021","url":"https://publications.europa.eu/resource/celex/02000L0039-20210520"},{"id":"r60-2026-09-30-d918-oehha-prop65-list-csv-own-url","type":"regulatory","title":"OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26)","url":"https://oehha.ca.gov/sites/default/files/media/2025-01/p65chemicalslist.csv"},{"id":"pubchem-exp-cameo-chemicals-cid-222","type":"database","title":"CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 222; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/222/JSON?heading=Experimental+Properties"},{"id":"pubchem-exp-hazardous-substances-data-bank-cid-222","type":"database","title":"Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 222; where-to-look, not a source of this value)","year":2026,"url":"https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/222/JSON?heading=Experimental+Properties"}],"sources_scope":"context","derived_markers":[],"warnings":["unmapped_classification:OSHA:pel 50 ppm","unmapped_classification:NIOSH:rel 25 ppm","unmapped_classification:NIOSH:idlh 300 ppm","unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: negativ","unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: negativ","unmapped_classification:ECHA (CLP Annex VI):skin irritation: skin corr. 1b","unmapped_classification:Canada, as recorded by ToxValDB:skin irritation: skin corrosion/irritation - categ","unmapped_classification:Japan, as recorded by ToxValDB:eye irritation: category 1 (score: very high)","unmapped_classification:Japan, as recorded by ToxValDB:skin irritation: category 1 (score: very high)","unmapped_classification:DOSH Malaysia (ICOP):eye irritation: eye dam. 1","unmapped_classification:DOSH Malaysia (ICOP):skin irritation: skin corr. 1b","unmapped_classification:New Zealand, as recorded by ToxValDB:eye irritation: category 8.3a (category 1) (score:","unmapped_classification:New Zealand, as recorded by ToxValDB:skin irritation: category 8.2b (category 1b) (scor","unmapped_classification:ECHA eChemPortal, as recorded by ToxValDB:skin irritation: in vivo: corrosive (score: very h","unmapped_classification:ASHRAE 34:b2l — higher toxicity, mildly flammable","unmapped_classification:OSHA:pel 50 ppm twa. stel not established. idlh 300 ppm","unmapped_classification:EPA RMP:risk management plan required for facilities with ","unmapped_classification:IIAR:international institute of ammonia refrigeration s","unmapped_classification:PSI OSHA:process safety management applies at facilities >1","unmapped_classification:EU SEVESO:seveso iii directive applies at >50 tonnes (lower ","unmapped_classification:DOT HAZMAT:un1005, toxic gas, class 2.3 (8)","single_source_warning"],"meta":{"synthesis_version":"1.1.0","config_version":"1.1.0","n_sources":1,"db_version":53,"warnings":["unmapped_classification:OSHA:pel 50 ppm","unmapped_classification:NIOSH:rel 25 ppm","unmapped_classification:NIOSH:idlh 300 ppm","unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: negativ","unmapped_classification:US EPA (CompTox genotoxicity summary):epa comptox computed genotoxicity summary: negativ","unmapped_classification:ECHA (CLP Annex VI):skin irritation: skin corr. 1b","unmapped_classification:Canada, as recorded by ToxValDB:skin irritation: skin corrosion/irritation - categ","unmapped_classification:Japan, as recorded by ToxValDB:eye irritation: category 1 (score: very high)","unmapped_classification:Japan, as recorded by ToxValDB:skin irritation: category 1 (score: very high)","unmapped_classification:DOSH Malaysia (ICOP):eye irritation: eye dam. 1","unmapped_classification:DOSH Malaysia (ICOP):skin irritation: skin corr. 1b","unmapped_classification:New Zealand, as recorded by ToxValDB:eye irritation: category 8.3a (category 1) (score:","unmapped_classification:New Zealand, as recorded by ToxValDB:skin irritation: category 8.2b (category 1b) (scor","unmapped_classification:ECHA eChemPortal, as recorded by ToxValDB:skin irritation: in vivo: corrosive (score: very h","unmapped_classification:ASHRAE 34:b2l — higher toxicity, mildly flammable","unmapped_classification:OSHA:pel 50 ppm twa. stel not established. idlh 300 ppm","unmapped_classification:EPA RMP:risk management plan required for facilities with ","unmapped_classification:IIAR:international institute of ammonia refrigeration s","unmapped_classification:PSI OSHA:process safety management applies at facilities >1","unmapped_classification:EU SEVESO:seveso iii directive applies at >50 tonnes (lower ","unmapped_classification:DOT HAZMAT:un1005, toxic gas, class 2.3 (8)"]},"schema":"synthesis","_notice":"ALETHEIA output is reference data, not professional advice. Not a substitute for primary agency sources or qualified professionals. See https://aletheia.holisticquality.io/disclaimer.","_disclaimer_url":"https://aletheia.holisticquality.io/disclaimer","available_contexts":["human_adult","human_child","dog","cat","exposure_inhalation","exposure_dermal","aquatic_life","human_teen","human_elderly","human_infant","human_pregnant","exposure_ingestion","exposure_ocular","occupational_exposure"]}